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Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China.
J Zhejiang Univ Sci B. 2013 Mar; 14(3):240-6.JZ

Abstract

OBJECTIVE

Weed pollens are common sources of allergens worldwide. The prevalence of weed pollen sensitization is not yet fully known in China. The purpose of this study was to investigate the prevalence of sensitization to weed allergens from Artemisia, Ambrosia, and Humulus in northern China.

METHODS

A total of 1144 subjects (aged from 5 to 68 years) visiting our clinic from June to October 2011 underwent intradermal testing using a panel of 25 allergen sources. Subjects with positive skin responses to any pollen were further tested for their serum concentrations of IgE antibodies against Artemisia vulgaris, Ambrosia artemisiifolia, and Humulus scandens, and against the purified allergens, Art v 1 and Amb a 1.

RESULTS

Of 1144 subjects, 170 had positive intradermal reactions to pollen and 144 donated serum for IgE testing. The prevalence of positive intradermal responses to pollens of Artemisia sieversiana, Artemisia annua, A. artemisiifolia, and H. scandens was 11.0%, 10.2%, 3.7%, and 6.6%, respectively. Among the intradermal positive subjects, the prevalence of specific IgE antigens to A. vulgaris was 58.3%, to A. artemisiifolia 14.7%, and to H. scandens 41.0%. The prevalence of specific IgE antigens to the allergen Art v 1 was 46.9%, and to Amb a 1 was 11.2%. The correlation between the presence of IgE antibodies specific to A. vulgaris and to the Art v 1 antigen was very high. Subjects with A. artemisiifolia specific IgE also had A. vulgaris specific IgE, but with relatively high levels of A. vulgaris IgE antibodies. There were no correlations between the presence of IgE antibodies to H. scandens and A. vulgaris or to H. scandens and A. artemisiifolia.

CONCLUSIONS

The intradermal prevalence of weed pollen sensitization among allergic subjects in northern China is about 13.5%. Correlations of specific IgE antibodies suggest that pollen allergens from Artemisia and Humulus are independent sources for primary sensitization.

Authors+Show Affiliations

Department of Allergy, Tangshan Gongren Hospital, Tangshan, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23463767

Citation

Hao, Guo-dong, et al. "Prevalence of Sensitization to Weed Pollens of Humulus Scandens, Artemisia Vulgaris, and Ambrosia Artemisiifolia in Northern China." Journal of Zhejiang University. Science. B, vol. 14, no. 3, 2013, pp. 240-6.
Hao GD, Zheng YW, Gjesing B, et al. Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China. J Zhejiang Univ Sci B. 2013;14(3):240-6.
Hao, G. D., Zheng, Y. W., Gjesing, B., Kong, X. A., Wang, J. Y., Song, Z. J., Lai, X. X., Zhong, N. S., & Spangfort, M. D. (2013). Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China. Journal of Zhejiang University. Science. B, 14(3), 240-6. https://doi.org/10.1631/jzus.B1200185
Hao GD, et al. Prevalence of Sensitization to Weed Pollens of Humulus Scandens, Artemisia Vulgaris, and Ambrosia Artemisiifolia in Northern China. J Zhejiang Univ Sci B. 2013;14(3):240-6. PubMed PMID: 23463767.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence of sensitization to weed pollens of Humulus scandens, Artemisia vulgaris, and Ambrosia artemisiifolia in northern China. AU - Hao,Guo-dong, AU - Zheng,Yi-wu, AU - Gjesing,Birgitte, AU - Kong,Xing-ai, AU - Wang,Jing-yuan, AU - Song,Zhi-jing, AU - Lai,Xu-xin, AU - Zhong,Nan-shan, AU - Spangfort,Michael D, PY - 2013/3/7/entrez PY - 2013/3/7/pubmed PY - 2013/8/31/medline SP - 240 EP - 6 JF - Journal of Zhejiang University. Science. B JO - J Zhejiang Univ Sci B VL - 14 IS - 3 N2 - OBJECTIVE: Weed pollens are common sources of allergens worldwide. The prevalence of weed pollen sensitization is not yet fully known in China. The purpose of this study was to investigate the prevalence of sensitization to weed allergens from Artemisia, Ambrosia, and Humulus in northern China. METHODS: A total of 1144 subjects (aged from 5 to 68 years) visiting our clinic from June to October 2011 underwent intradermal testing using a panel of 25 allergen sources. Subjects with positive skin responses to any pollen were further tested for their serum concentrations of IgE antibodies against Artemisia vulgaris, Ambrosia artemisiifolia, and Humulus scandens, and against the purified allergens, Art v 1 and Amb a 1. RESULTS: Of 1144 subjects, 170 had positive intradermal reactions to pollen and 144 donated serum for IgE testing. The prevalence of positive intradermal responses to pollens of Artemisia sieversiana, Artemisia annua, A. artemisiifolia, and H. scandens was 11.0%, 10.2%, 3.7%, and 6.6%, respectively. Among the intradermal positive subjects, the prevalence of specific IgE antigens to A. vulgaris was 58.3%, to A. artemisiifolia 14.7%, and to H. scandens 41.0%. The prevalence of specific IgE antigens to the allergen Art v 1 was 46.9%, and to Amb a 1 was 11.2%. The correlation between the presence of IgE antibodies specific to A. vulgaris and to the Art v 1 antigen was very high. Subjects with A. artemisiifolia specific IgE also had A. vulgaris specific IgE, but with relatively high levels of A. vulgaris IgE antibodies. There were no correlations between the presence of IgE antibodies to H. scandens and A. vulgaris or to H. scandens and A. artemisiifolia. CONCLUSIONS: The intradermal prevalence of weed pollen sensitization among allergic subjects in northern China is about 13.5%. Correlations of specific IgE antibodies suggest that pollen allergens from Artemisia and Humulus are independent sources for primary sensitization. SN - 1862-1783 UR - https://www.unboundmedicine.com/medline/citation/23463767/Prevalence_of_sensitization_to_weed_pollens_of_Humulus_scandens_Artemisia_vulgaris_and_Ambrosia_artemisiifolia_in_northern_China_ L2 - http://www.jzus.zju.edu.cn/article.php?doi=10.1631/jzus.B1200185 DB - PRIME DP - Unbound Medicine ER -