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Central alveolar hypoventilation (Ondine's curse) caused by megadolichobasilar artery.
J Stroke Cerebrovasc Dis. 2014 Feb; 23(2):390-2.JS

Abstract

Central alveolar hypoventilation (CAH) syndrome is a clinical condition that is characterized by the loss of automatic breathing, particularly during sleep. Most forms in adults are caused by brainstem ischemia, mass, infection, demyelinating disease, or anoxic-ischemic damage. We present a case of a fatal symptomatic acquired CAH syndrome caused by megadolichobasilar artery. A 62-year-old man with pre-existing vascular dementia suffered an acute posterior stroke. During stroke care, long episodes of hypopnea and apnea were observed which responded well to verbal reminders. During an unobserved episode, the patient was found unresponsive, with chemical signs of prolonged hypoventilation not explainable by cardiopulmonary disease. A diaphragmatic pacemaker, assisted ventilation, and repeated resuscitation were refused by the patient, who died some days later. CAH is a rare complication that can occur in patients with megadolichobasilar artery.

Authors+Show Affiliations

Department of Neurology, Municipal Hospital Landshut, Landshut, Germany. Electronic address: josef.heckmann@klinikum-landshut.de.Department of Radiology, Municipal Hospital Landshut, Landshut, Germany.

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

23465843

Citation

Heckmann, Josef G., and Stefan Ernst. "Central Alveolar Hypoventilation (Ondine's Curse) Caused By Megadolichobasilar Artery." Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, vol. 23, no. 2, 2014, pp. 390-2.
Heckmann JG, Ernst S. Central alveolar hypoventilation (Ondine's curse) caused by megadolichobasilar artery. J Stroke Cerebrovasc Dis. 2014;23(2):390-2.
Heckmann, J. G., & Ernst, S. (2014). Central alveolar hypoventilation (Ondine's curse) caused by megadolichobasilar artery. Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association, 23(2), 390-2. https://doi.org/10.1016/j.jstrokecerebrovasdis.2013.02.003
Heckmann JG, Ernst S. Central Alveolar Hypoventilation (Ondine's Curse) Caused By Megadolichobasilar Artery. J Stroke Cerebrovasc Dis. 2014;23(2):390-2. PubMed PMID: 23465843.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Central alveolar hypoventilation (Ondine's curse) caused by megadolichobasilar artery. AU - Heckmann,Josef G, AU - Ernst,Stefan, Y1 - 2013/03/01/ PY - 2012/09/24/received PY - 2013/02/01/revised PY - 2013/02/02/accepted PY - 2013/3/8/entrez PY - 2013/3/8/pubmed PY - 2014/9/30/medline KW - Brainstem affection KW - Ondine's curse KW - central alveolar hypoventilation KW - megadolichobasilar artery SP - 390 EP - 2 JF - Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association JO - J Stroke Cerebrovasc Dis VL - 23 IS - 2 N2 - Central alveolar hypoventilation (CAH) syndrome is a clinical condition that is characterized by the loss of automatic breathing, particularly during sleep. Most forms in adults are caused by brainstem ischemia, mass, infection, demyelinating disease, or anoxic-ischemic damage. We present a case of a fatal symptomatic acquired CAH syndrome caused by megadolichobasilar artery. A 62-year-old man with pre-existing vascular dementia suffered an acute posterior stroke. During stroke care, long episodes of hypopnea and apnea were observed which responded well to verbal reminders. During an unobserved episode, the patient was found unresponsive, with chemical signs of prolonged hypoventilation not explainable by cardiopulmonary disease. A diaphragmatic pacemaker, assisted ventilation, and repeated resuscitation were refused by the patient, who died some days later. CAH is a rare complication that can occur in patients with megadolichobasilar artery. SN - 1532-8511 UR - https://www.unboundmedicine.com/medline/citation/23465843/Central_alveolar_hypoventilation__Ondine's_curse__caused_by_megadolichobasilar_artery_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1052-3057(13)00031-1 DB - PRIME DP - Unbound Medicine ER -