Tags

Type your tag names separated by a space and hit enter

The clinical spectrum of sport-related traumatic brain injury.

Abstract

Acute and chronic sports-related traumatic brain injuries (TBIs) are a substantial public health concern. Various types of acute TBI can occur in sport, but detection and management of cerebral concussion is of greatest importance as mismanagement of this syndrome can lead to persistent or chronic postconcussion syndrome (CPCS) or diffuse cerebral swelling. Chronic TBI encompasses a spectrum of disorders that are associated with long-term consequences of brain injury, including chronic traumatic encephalopathy (CTE), dementia pugilistica, post-traumatic parkinsonism, post-traumatic dementia and CPCS. CTE is the prototype of chronic TBI, but can only be definitively diagnosed at autopsy as no reliable biomarkers of this disorder are available. Whether CTE shares neuropathological features with CPCS is unknown. Evidence suggests that participation in contact-collision sports may increase the risk of neurodegenerative disorders such as Alzheimer disease, but the data are conflicting. In this Review, the spectrum of acute and chronic sport-related TBI is discussed, highlighting how examination of athletes involved in high-impact sports has advanced our understanding of pathology of brain injury and enabled improvements in detection and diagnosis of sport-related TBI.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    Burke Rehabilitation Hospital, 785 Mamaroneck Avenue, White Plains, New York, 10605 NY, USA. bjordan@burke.org

    Source

    Nature reviews. Neurology 9:4 2013 Apr pg 222-30

    MeSH

    Athletic Injuries
    Brain
    Brain Edema
    Brain Injuries
    Dementia
    Disease Progression
    Humans
    Neurodegenerative Diseases
    Post-Concussion Syndrome

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    23478462

    Citation

    Jordan, Barry D.. "The Clinical Spectrum of Sport-related Traumatic Brain Injury." Nature Reviews. Neurology, vol. 9, no. 4, 2013, pp. 222-30.
    Jordan BD. The clinical spectrum of sport-related traumatic brain injury. Nat Rev Neurol. 2013;9(4):222-30.
    Jordan, B. D. (2013). The clinical spectrum of sport-related traumatic brain injury. Nature Reviews. Neurology, 9(4), pp. 222-30. doi:10.1038/nrneurol.2013.33.
    Jordan BD. The Clinical Spectrum of Sport-related Traumatic Brain Injury. Nat Rev Neurol. 2013;9(4):222-30. PubMed PMID: 23478462.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - The clinical spectrum of sport-related traumatic brain injury. A1 - Jordan,Barry D, Y1 - 2013/03/12/ PY - 2013/3/13/entrez PY - 2013/3/13/pubmed PY - 2013/10/1/medline SP - 222 EP - 30 JF - Nature reviews. Neurology JO - Nat Rev Neurol VL - 9 IS - 4 N2 - Acute and chronic sports-related traumatic brain injuries (TBIs) are a substantial public health concern. Various types of acute TBI can occur in sport, but detection and management of cerebral concussion is of greatest importance as mismanagement of this syndrome can lead to persistent or chronic postconcussion syndrome (CPCS) or diffuse cerebral swelling. Chronic TBI encompasses a spectrum of disorders that are associated with long-term consequences of brain injury, including chronic traumatic encephalopathy (CTE), dementia pugilistica, post-traumatic parkinsonism, post-traumatic dementia and CPCS. CTE is the prototype of chronic TBI, but can only be definitively diagnosed at autopsy as no reliable biomarkers of this disorder are available. Whether CTE shares neuropathological features with CPCS is unknown. Evidence suggests that participation in contact-collision sports may increase the risk of neurodegenerative disorders such as Alzheimer disease, but the data are conflicting. In this Review, the spectrum of acute and chronic sport-related TBI is discussed, highlighting how examination of athletes involved in high-impact sports has advanced our understanding of pathology of brain injury and enabled improvements in detection and diagnosis of sport-related TBI. SN - 1759-4766 UR - https://www.unboundmedicine.com/medline/citation/23478462/The_clinical_spectrum_of_sport_related_traumatic_brain_injury_ L2 - http://dx.doi.org/10.1038/nrneurol.2013.33 DB - PRIME DP - Unbound Medicine ER -