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Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis.
Respir Med. 2013 May; 107(5):684-90.RM

Abstract

BACKGROUND

The beneficial role of exercise in maintaining health in patients with cystic fibrosis (CF) is well described. Few data exist on the effect of exercise on respiratory muscle function in patients with CF. Our objective was to compare respiratory muscle function indices in CF patients that regularly exercise with those CF patients that do not.

METHODS

This cross-sectional study assessed nutrition, pulmonary function and respiratory muscle function in 37 CF patients that undertook regular aerobic exercise and in a control group matched for age and gender which consisted of 44 CF patients that did not undertake regular exercise. Respiratory muscle function in CF was assessed by maximal inspiratory pressure (Pimax), maximal expiratory pressure (Pemax) and pressure-time index of the respiratory muscles (PTImus).

RESULTS

Median Pimax and Pemax were significantly higher in the exercise group compared to the control group (92 vs. 63 cm H2O and 94 vs. 64 cm H2O respectively). PTImus was significantly lower in the exercise group compared to the control group (0.089 vs. 0.121). Upper arm muscle area (UAMA) and mid-arm muscle circumference were significantly increased in the exercise group compared to the control group (2608 vs. 2178 mm2 and 23 vs. 21 cm respectively). UAMA was significantly related to Pimax in the exercising group.

CONCLUSIONS

These results suggest that CF patients that undertake regular aerobic exercise maintain higher indices of respiratory muscle strength and lower PTImus values, while increased UAMA values in exercising patients highlight the importance of muscular competence in respiratory muscle function in this population.

Authors+Show Affiliations

Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Hills Road, Cambridge CB2 0SW, UK. tdassios@upatras.grNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

23485096

Citation

Dassios, Theodore, et al. "Aerobic Exercise and Respiratory Muscle Strength in Patients With Cystic Fibrosis." Respiratory Medicine, vol. 107, no. 5, 2013, pp. 684-90.
Dassios T, Katelari A, Doudounakis S, et al. Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis. Respir Med. 2013;107(5):684-90.
Dassios, T., Katelari, A., Doudounakis, S., & Dimitriou, G. (2013). Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis. Respiratory Medicine, 107(5), 684-90. https://doi.org/10.1016/j.rmed.2013.01.016
Dassios T, et al. Aerobic Exercise and Respiratory Muscle Strength in Patients With Cystic Fibrosis. Respir Med. 2013;107(5):684-90. PubMed PMID: 23485096.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Aerobic exercise and respiratory muscle strength in patients with cystic fibrosis. AU - Dassios,Theodore, AU - Katelari,Anna, AU - Doudounakis,Stavros, AU - Dimitriou,Gabriel, Y1 - 2013/02/26/ PY - 2012/09/19/received PY - 2013/01/18/revised PY - 2013/01/20/accepted PY - 2013/3/15/entrez PY - 2013/3/15/pubmed PY - 2013/10/1/medline SP - 684 EP - 90 JF - Respiratory medicine JO - Respir Med VL - 107 IS - 5 N2 - BACKGROUND: The beneficial role of exercise in maintaining health in patients with cystic fibrosis (CF) is well described. Few data exist on the effect of exercise on respiratory muscle function in patients with CF. Our objective was to compare respiratory muscle function indices in CF patients that regularly exercise with those CF patients that do not. METHODS: This cross-sectional study assessed nutrition, pulmonary function and respiratory muscle function in 37 CF patients that undertook regular aerobic exercise and in a control group matched for age and gender which consisted of 44 CF patients that did not undertake regular exercise. Respiratory muscle function in CF was assessed by maximal inspiratory pressure (Pimax), maximal expiratory pressure (Pemax) and pressure-time index of the respiratory muscles (PTImus). RESULTS: Median Pimax and Pemax were significantly higher in the exercise group compared to the control group (92 vs. 63 cm H2O and 94 vs. 64 cm H2O respectively). PTImus was significantly lower in the exercise group compared to the control group (0.089 vs. 0.121). Upper arm muscle area (UAMA) and mid-arm muscle circumference were significantly increased in the exercise group compared to the control group (2608 vs. 2178 mm2 and 23 vs. 21 cm respectively). UAMA was significantly related to Pimax in the exercising group. CONCLUSIONS: These results suggest that CF patients that undertake regular aerobic exercise maintain higher indices of respiratory muscle strength and lower PTImus values, while increased UAMA values in exercising patients highlight the importance of muscular competence in respiratory muscle function in this population. SN - 1532-3064 UR - https://www.unboundmedicine.com/medline/citation/23485096/Aerobic_exercise_and_respiratory_muscle_strength_in_patients_with_cystic_fibrosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0954-6111(13)00042-5 DB - PRIME DP - Unbound Medicine ER -