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Apathy is associated with activities of daily living ability in Parkinson's disease.
Dement Geriatr Cogn Disord. 2013; 35(5-6):249-55.DG

Abstract

BACKGROUND

Neuropsychiatric symptoms and impairment in performing activities of daily living (ADL) in patients with Parkinson's disease (PD) are strong predictors of the overall caregiver burden and they increase the risk for nursing home admission of the patients. The purpose of the present study was to assess the association of neuropsychiatric symptoms and ADL functions in PD.

METHODS

A total of 73 community-dwelling PD patients were studied. The mean age of the patient group was 65 years and the mean disease duration was 9 years. The Neuropsychiatric Inventory was used to measure neuropsychiatric symptoms, and ADL abilities were measured by the Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory.

RESULTS

The prevalence of neuropsychiatric symptoms in patients with PD was 73%. The most common symptoms were depression, anxiety, irritability, apathy and agitation. ADL ability correlated significantly with apathy (p < 0.002) even when adjusted for motor symptoms.

CONCLUSION

Apathy was significantly associated with ADL in PD. The result indicates that more attention should be paid to identifying apathy and targeting therapeutic interventions.

Authors+Show Affiliations

The Outpatient Ward of Neuropsychiatry, Turku University Central Hospital, Turku, Finland. sari.laatu@tyks.fiNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23485683

Citation

Laatu, S, et al. "Apathy Is Associated With Activities of Daily Living Ability in Parkinson's Disease." Dementia and Geriatric Cognitive Disorders, vol. 35, no. 5-6, 2013, pp. 249-55.
Laatu S, Karrasch M, Martikainen K, et al. Apathy is associated with activities of daily living ability in Parkinson's disease. Dement Geriatr Cogn Disord. 2013;35(5-6):249-55.
Laatu, S., Karrasch, M., Martikainen, K., & Marttila, R. (2013). Apathy is associated with activities of daily living ability in Parkinson's disease. Dementia and Geriatric Cognitive Disorders, 35(5-6), 249-55. https://doi.org/10.1159/000347129
Laatu S, et al. Apathy Is Associated With Activities of Daily Living Ability in Parkinson's Disease. Dement Geriatr Cogn Disord. 2013;35(5-6):249-55. PubMed PMID: 23485683.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Apathy is associated with activities of daily living ability in Parkinson's disease. AU - Laatu,S, AU - Karrasch,M, AU - Martikainen,K, AU - Marttila,R, Y1 - 2013/03/07/ PY - 2012/12/21/accepted PY - 2013/3/15/entrez PY - 2013/3/15/pubmed PY - 2013/12/24/medline SP - 249 EP - 55 JF - Dementia and geriatric cognitive disorders JO - Dement Geriatr Cogn Disord VL - 35 IS - 5-6 N2 - BACKGROUND: Neuropsychiatric symptoms and impairment in performing activities of daily living (ADL) in patients with Parkinson's disease (PD) are strong predictors of the overall caregiver burden and they increase the risk for nursing home admission of the patients. The purpose of the present study was to assess the association of neuropsychiatric symptoms and ADL functions in PD. METHODS: A total of 73 community-dwelling PD patients were studied. The mean age of the patient group was 65 years and the mean disease duration was 9 years. The Neuropsychiatric Inventory was used to measure neuropsychiatric symptoms, and ADL abilities were measured by the Alzheimer's Disease Cooperative Study-Activities of Daily Living Inventory. RESULTS: The prevalence of neuropsychiatric symptoms in patients with PD was 73%. The most common symptoms were depression, anxiety, irritability, apathy and agitation. ADL ability correlated significantly with apathy (p < 0.002) even when adjusted for motor symptoms. CONCLUSION: Apathy was significantly associated with ADL in PD. The result indicates that more attention should be paid to identifying apathy and targeting therapeutic interventions. SN - 1421-9824 UR - https://www.unboundmedicine.com/medline/citation/23485683/Apathy_is_associated_with_activities_of_daily_living_ability_in_Parkinson's_disease_ L2 - https://www.karger.com?DOI=10.1159/000347129 DB - PRIME DP - Unbound Medicine ER -