Tags

Type your tag names separated by a space and hit enter

Intestinal lengthening and nutritional outcomes in children with short bowel syndrome.
Am J Surg. 2013 May; 205(5):576-80.AJ

Abstract

BACKGROUND

Intestinal lengthening remains a treatment option in pediatric short bowel syndrome. However, clinical indications and nutritional outcomes from bowel lengthening are not well defined.

METHODS

A retrospective review of a prospective database was conducted of patients who underwent bowel lengthening using serial transverse enteroplasty (STEP) at a single center.

RESULTS

Sixteen children who underwent 19 STEP procedures were identified. STEP increased median small bowel length from 84 cm (range, 19 to 295 cm) to 103 cm (range, 24 to 375 cm) (P = .0001). Caloric provisions from parenteral nutrition were decreased after STEP (69% vs 0%, P < .01). Of 15 subjects in the nutritional analysis, 12 (80%) had improved enteral tolerance, and 9 (60%) achieved enteral autonomy after STEP. Six STEP procedures were not associated with improvements in enteral nutrition, and 5 (83%) were performed in children with gastroschisis.

CONCLUSIONS

A majority of children with short bowel syndrome were weaned off parenteral nutrition after STEP. Gastroschisis may portend a less optimal outcome from the procedure.

Authors+Show Affiliations

Division of Pediatric General and Thoracic Surgery, Seattle Children's Hospital and University of Washington School of Medicine, Seattle, WA, USA. patrick.javid@seattlechildrens.orgNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Evaluation Study
Journal Article

Language

eng

PubMed ID

23497916

Citation

Javid, Patrick J., et al. "Intestinal Lengthening and Nutritional Outcomes in Children With Short Bowel Syndrome." American Journal of Surgery, vol. 205, no. 5, 2013, pp. 576-80.
Javid PJ, Sanchez SE, Horslen SP, et al. Intestinal lengthening and nutritional outcomes in children with short bowel syndrome. Am J Surg. 2013;205(5):576-80.
Javid, P. J., Sanchez, S. E., Horslen, S. P., & Healey, P. J. (2013). Intestinal lengthening and nutritional outcomes in children with short bowel syndrome. American Journal of Surgery, 205(5), 576-80. https://doi.org/10.1016/j.amjsurg.2013.01.013
Javid PJ, et al. Intestinal Lengthening and Nutritional Outcomes in Children With Short Bowel Syndrome. Am J Surg. 2013;205(5):576-80. PubMed PMID: 23497916.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intestinal lengthening and nutritional outcomes in children with short bowel syndrome. AU - Javid,Patrick J, AU - Sanchez,Sabrina E, AU - Horslen,Simon P, AU - Healey,Patrick J, Y1 - 2013/03/14/ PY - 2012/10/26/received PY - 2013/01/08/revised PY - 2013/01/14/accepted PY - 2013/3/19/entrez PY - 2013/3/19/pubmed PY - 2013/6/14/medline SP - 576 EP - 80 JF - American journal of surgery JO - Am J Surg VL - 205 IS - 5 N2 - BACKGROUND: Intestinal lengthening remains a treatment option in pediatric short bowel syndrome. However, clinical indications and nutritional outcomes from bowel lengthening are not well defined. METHODS: A retrospective review of a prospective database was conducted of patients who underwent bowel lengthening using serial transverse enteroplasty (STEP) at a single center. RESULTS: Sixteen children who underwent 19 STEP procedures were identified. STEP increased median small bowel length from 84 cm (range, 19 to 295 cm) to 103 cm (range, 24 to 375 cm) (P = .0001). Caloric provisions from parenteral nutrition were decreased after STEP (69% vs 0%, P < .01). Of 15 subjects in the nutritional analysis, 12 (80%) had improved enteral tolerance, and 9 (60%) achieved enteral autonomy after STEP. Six STEP procedures were not associated with improvements in enteral nutrition, and 5 (83%) were performed in children with gastroschisis. CONCLUSIONS: A majority of children with short bowel syndrome were weaned off parenteral nutrition after STEP. Gastroschisis may portend a less optimal outcome from the procedure. SN - 1879-1883 UR - https://www.unboundmedicine.com/medline/citation/23497916/Intestinal_lengthening_and_nutritional_outcomes_in_children_with_short_bowel_syndrome_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9610(13)00112-8 DB - PRIME DP - Unbound Medicine ER -