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Evaluation and treatment of esophageal varices in the cirrhotic patient.
Isr Med Assoc J. 2013 Feb; 15(2):109-15.IM

Abstract

Portal hypertension is the leading cause of morbidity and mortality in liver cirrhosis. Complications of portal hypertension in cirrhotic patients include esophageal and gastric varices, portal hypertensive gastropathy, ascites, hepatorenal syndrome, hepatopulmonary syndrome and portopulmonary hypertension. The hepatic venous pressure gradient should be at least 10 mmHg for esophageal varices to appear, and more than 12 mmHg for acute esophageal variceal bleeding. This article reviews the pathophysiology responsible for portal hypertension and its complications, and the treatments used for esophageal varices in the setting of primary and secondary prophylaxis and during active bleeding.

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Authors+Show Affiliations

Ashkenazi E
Liver Unit, Carmel Medical Center, Haifa, Israel. eyalas@clalit.org.il
Kovalev Y
No affiliation info available
Zuckerman E
No affiliation info available

MeSH

Esophageal and Gastric VaricesHumansHypertension, PortalLiver CirrhosisPrimary PreventionSecondary Prevention

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23516775

Citation

Ashkenazi, Eyal, et al. "Evaluation and Treatment of Esophageal Varices in the Cirrhotic Patient." The Israel Medical Association Journal : IMAJ, vol. 15, no. 2, 2013, pp. 109-15.
Ashkenazi E, Kovalev Y, Zuckerman E. Evaluation and treatment of esophageal varices in the cirrhotic patient. Isr Med Assoc J. 2013;15(2):109-15.
Ashkenazi, E., Kovalev, Y., & Zuckerman, E. (2013). Evaluation and treatment of esophageal varices in the cirrhotic patient. The Israel Medical Association Journal : IMAJ, 15(2), 109-15.
Ashkenazi E, Kovalev Y, Zuckerman E. Evaluation and Treatment of Esophageal Varices in the Cirrhotic Patient. Isr Med Assoc J. 2013;15(2):109-15. PubMed PMID: 23516775.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Evaluation and treatment of esophageal varices in the cirrhotic patient. AU - Ashkenazi,Eyal, AU - Kovalev,Yulia, AU - Zuckerman,Eli, PY - 2013/3/23/entrez PY - 2013/3/23/pubmed PY - 2013/6/5/medline SP - 109 EP - 15 JF - The Israel Medical Association journal : IMAJ JO - Isr Med Assoc J VL - 15 IS - 2 N2 - Portal hypertension is the leading cause of morbidity and mortality in liver cirrhosis. Complications of portal hypertension in cirrhotic patients include esophageal and gastric varices, portal hypertensive gastropathy, ascites, hepatorenal syndrome, hepatopulmonary syndrome and portopulmonary hypertension. The hepatic venous pressure gradient should be at least 10 mmHg for esophageal varices to appear, and more than 12 mmHg for acute esophageal variceal bleeding. This article reviews the pathophysiology responsible for portal hypertension and its complications, and the treatments used for esophageal varices in the setting of primary and secondary prophylaxis and during active bleeding. SN - 1565-1088 UR - https://www.unboundmedicine.com/medline/citation/23516775/Evaluation_and_treatment_of_esophageal_varices_in_the_cirrhotic_patient_ L2 - http://www.ima.org.il/IMAJ/ViewArticle.aspx?year=2013&month=02&page=109 DB - PRIME DP - Unbound Medicine ER -