Prime

Type your tag names separated by a space and hit enter

Additive effects between prematurity and postnatal risk factors of suicidal behavior.

Abstract

BACKGROUND

Pre- and perinatal insults increase suicide risk. The main objective of the present study is to investigate if prematurity interacts in an additive fashion with postnatal risk factors of suicidal behavior.

METHOD

Sample and procedure: 857 adult suicide attempters consecutively hospitalized for a suicide attempt were included. Studied characteristics of suicide attempts included use of a violent mean, age at first suicide attempt, and number of suicide attempts. Risk factors of suicidal behavior included indexes of pre- and perinatal adversity, childhood maltreatment as measured with the Childhood Trauma Questionnaire, personality traits as measured with the Tridimensional Personality Questionnaire, and family history of suicidal behavior.

STATISTICAL ANALYSES

Comparisons between the different patterns of suicide attempts characteristics were made using logistic regression with crude and adjusted odds ratios and 95% confidence intervals.

RESULTS

The risk of violent suicide attempts increased significantly in patients born prematurely (OR [95%] = 2.38[1.12-5.08]). There were additive effects for very preterm birth and 1) emotional abuse (OR [95% CI] = 4.52 [1.75-11.60]), 2) novelty seeking (OR [95% CI] = 8.92[3.09-25.7]), and 3) harm avoidance (OR [95% CI] = 5.81 [2.43-13.90]) on the age at first suicide attempt, after adjustment for potential confounders.

CONCLUSIONS

Very preterm birth appears to be the first step in a cascade of stressors across lifetime, which affects the risk and the severity of suicidal behavior. Furthermore, very preterm birth, childhood maltreatment and personality traits have additive effects that influence the age at onset of suicide attempt. Our findings may have potential consequences for preventive policies.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Psychiatry, IIS-Puerta de Hierro Hospital, CIBERSAM, Madrid, Spain. hmblasco@yahoo.es

    , , , , , ,

    Source

    Journal of psychiatric research 47:7 2013 Jul pg 937-43

    MeSH

    Adolescent
    Adult
    Age Factors
    Aged
    Aged, 80 and over
    Aging, Premature
    Child Abuse
    Female
    Humans
    Male
    Maternal Age
    Middle Aged
    Personality
    Pregnancy
    Prenatal Exposure Delayed Effects
    Risk Factors
    Sex Offenses
    Suicide, Attempted
    Violence
    Young Adult

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    23535031

    Citation

    TY - JOUR T1 - Additive effects between prematurity and postnatal risk factors of suicidal behavior. AU - Blasco-Fontecilla,Hilario, AU - Jaussent,Isabelle, AU - Olié,Emilie, AU - Garcia,Enrique Baca, AU - Beziat,Severine, AU - Malafosse,Alain, AU - Guillaume,Sebastien, AU - Courtet,Philippe, Y1 - 2013/03/25/ PY - 2012/11/2/received PY - 2013/2/20/revised PY - 2013/2/26/accepted PY - 2013/3/25/aheadofprint PY - 2013/3/29/entrez PY - 2013/3/29/pubmed PY - 2013/12/16/medline SP - 937 EP - 43 JF - Journal of psychiatric research JO - J Psychiatr Res VL - 47 IS - 7 N2 - BACKGROUND: Pre- and perinatal insults increase suicide risk. The main objective of the present study is to investigate if prematurity interacts in an additive fashion with postnatal risk factors of suicidal behavior. METHOD: Sample and procedure: 857 adult suicide attempters consecutively hospitalized for a suicide attempt were included. Studied characteristics of suicide attempts included use of a violent mean, age at first suicide attempt, and number of suicide attempts. Risk factors of suicidal behavior included indexes of pre- and perinatal adversity, childhood maltreatment as measured with the Childhood Trauma Questionnaire, personality traits as measured with the Tridimensional Personality Questionnaire, and family history of suicidal behavior. STATISTICAL ANALYSES: Comparisons between the different patterns of suicide attempts characteristics were made using logistic regression with crude and adjusted odds ratios and 95% confidence intervals. RESULTS: The risk of violent suicide attempts increased significantly in patients born prematurely (OR [95%] = 2.38[1.12-5.08]). There were additive effects for very preterm birth and 1) emotional abuse (OR [95% CI] = 4.52 [1.75-11.60]), 2) novelty seeking (OR [95% CI] = 8.92[3.09-25.7]), and 3) harm avoidance (OR [95% CI] = 5.81 [2.43-13.90]) on the age at first suicide attempt, after adjustment for potential confounders. CONCLUSIONS: Very preterm birth appears to be the first step in a cascade of stressors across lifetime, which affects the risk and the severity of suicidal behavior. Furthermore, very preterm birth, childhood maltreatment and personality traits have additive effects that influence the age at onset of suicide attempt. Our findings may have potential consequences for preventive policies. SN - 1879-1379 UR - https://www.unboundmedicine.com/medline/citation/23535031/Additive_effects_between_prematurity_and_postnatal_risk_factors_of_suicidal_behavior_ L2 - http://linkinghub.elsevier.com/retrieve/pii/S0022-3956(13)00083-6 ER -