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Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic.
Clin Vaccine Immunol. 2013 May; 20(5):759-60.CV

Abstract

In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis.

Links

Publisher Full Text
ncbi.nlm.nih.gov
cvi.asm.org
PMC Free PDF

Authors+Show Affiliations

James GL
Emergency Department, Royal Darwin Hospital, Darwin, Northern Territory, Australia.
Delaney B
No affiliation info available
Ward L
No affiliation info available
Freeman K
No affiliation info available
Mayo M
No affiliation info available
Currie BJ
No affiliation info available

MeSH

AdultAntibodies, BacterialAustraliaBurkholderia pseudomalleiFemaleHemagglutination TestsHumansMaleMelioidosisMiddle AgedSeroepidemiologic StudiesYoung Adult

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23536689

Citation

James, Gemma L., et al. "Surprisingly Low Seroprevalence of Burkholderia Pseudomallei in Exposed Healthy Adults in the Darwin Region of Tropical Australia Where Melioidosis Is Highly Endemic." Clinical and Vaccine Immunology : CVI, vol. 20, no. 5, 2013, pp. 759-60.
James GL, Delaney B, Ward L, et al. Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic. Clin Vaccine Immunol. 2013;20(5):759-60.
James, G. L., Delaney, B., Ward, L., Freeman, K., Mayo, M., & Currie, B. J. (2013). Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic. Clinical and Vaccine Immunology : CVI, 20(5), 759-60. https://doi.org/10.1128/CVI.00021-13
James GL, et al. Surprisingly Low Seroprevalence of Burkholderia Pseudomallei in Exposed Healthy Adults in the Darwin Region of Tropical Australia Where Melioidosis Is Highly Endemic. Clin Vaccine Immunol. 2013;20(5):759-60. PubMed PMID: 23536689.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surprisingly low seroprevalence of Burkholderia pseudomallei in exposed healthy adults in the Darwin region of tropical Australia where melioidosis is highly endemic. AU - James,Gemma L, AU - Delaney,Ben, AU - Ward,Linda, AU - Freeman,Kevin, AU - Mayo,Mark, AU - Currie,Bart J, Y1 - 2013/03/27/ PY - 2013/3/29/entrez PY - 2013/3/29/pubmed PY - 2014/2/4/medline SP - 759 EP - 60 JF - Clinical and vaccine immunology : CVI JO - Clin. Vaccine Immunol. VL - 20 IS - 5 N2 - In the Darwin region of Australia where melioidosis is highly endemic, only 11/354 (3%) healthy residents were seropositive by indirect hemagglutination assay, despite extensive exposure to Burkholderia pseudomallei. None developed melioidosis, but some described a prior self-limiting illness. This seropositivity rate is much lower than that seen in northeast Thailand, where melioidosis is similarly highly endemic, potentially reflecting important differences between these two locations in the epidemiology of melioidosis. SN - 1556-679X UR - https://www.unboundmedicine.com/medline/citation/23536689/Surprisingly_low_seroprevalence_of_Burkholderia_pseudomallei_in_exposed_healthy_adults_in_the_Darwin_region_of_tropical_Australia_where_melioidosis_is_highly_endemic_ L2 - http://cvi.asm.org/cgi/pmidlookup?view=long&pmid=23536689 DB - PRIME DP - Unbound Medicine ER -