Rhodium(III)-catalyzed direct selective C(5)-H oxidative annulations of 2-substituted imidazoles and alkynes by double C-H activation.Org Lett. 2013 Apr 19; 15(8):1878-81.OL
Abstract
Double C-H activations of C(5)-H and Csp(2)-H of 2-substituted N-vinyl- or arylimidazoles were realized without heteroatom-directing assistance by rhodium(III) catalyst. A subsequent oxidative annulation reaction with alkynes efficiently produced aza-fused heterocycles with high molecular complexity in low to excellent yields.
Links
MeSH
Pub Type(s)
Journal Article
Research Support, Non-U.S. Gov't
Language
eng
PubMed ID
23537406
Citation
Huang, Ji-Rong, et al. "Rhodium(III)-catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-substituted Imidazoles and Alkynes By Double C-H Activation." Organic Letters, vol. 15, no. 8, 2013, pp. 1878-81.
Huang JR, Zhang QR, Qu CH, et al. Rhodium(III)-catalyzed direct selective C(5)-H oxidative annulations of 2-substituted imidazoles and alkynes by double C-H activation. Org Lett. 2013;15(8):1878-81.
Huang, J. R., Zhang, Q. R., Qu, C. H., Sun, X. H., Dong, L., & Chen, Y. C. (2013). Rhodium(III)-catalyzed direct selective C(5)-H oxidative annulations of 2-substituted imidazoles and alkynes by double C-H activation. Organic Letters, 15(8), 1878-81. https://doi.org/10.1021/ol400537b
Huang JR, et al. Rhodium(III)-catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-substituted Imidazoles and Alkynes By Double C-H Activation. Org Lett. 2013 Apr 19;15(8):1878-81. PubMed PMID: 23537406.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Rhodium(III)-catalyzed direct selective C(5)-H oxidative annulations of 2-substituted imidazoles and alkynes by double C-H activation.
AU - Huang,Ji-Rong,
AU - Zhang,Qian-Ru,
AU - Qu,Chuan-Hua,
AU - Sun,Xun-Hao,
AU - Dong,Lin,
AU - Chen,Ying-Chun,
Y1 - 2013/03/28/
PY - 2013/3/30/entrez
PY - 2013/3/30/pubmed
PY - 2013/8/31/medline
SP - 1878
EP - 81
JF - Organic letters
JO - Org Lett
VL - 15
IS - 8
N2 - Double C-H activations of C(5)-H and Csp(2)-H of 2-substituted N-vinyl- or arylimidazoles were realized without heteroatom-directing assistance by rhodium(III) catalyst. A subsequent oxidative annulation reaction with alkynes efficiently produced aza-fused heterocycles with high molecular complexity in low to excellent yields.
SN - 1523-7052
UR - https://www.unboundmedicine.com/medline/citation/23537406/Rhodium_III__catalyzed_direct_selective_C_5__H_oxidative_annulations_of_2_substituted_imidazoles_and_alkynes_by_double_C_H_activation_
L2 - https://doi.org/10.1021/ol400537b
DB - PRIME
DP - Unbound Medicine
ER -