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Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers.
Eur J Dermatol. 2013 Apr 01; 23(2):218-23.EJ

Abstract

The protozoan parasite Leishmania (Viannia) braziliensis is one of the main causes of cutaneous and mucocutaneous leishmaniasis in South America. Here, we describe three cases of L. (V.) braziliensis infection which were acquired during travelling in Bolivia, Peru or Paraguay and illustrate the phenotypic heterogeneity and therapeutic complexity of the disease. Two patients presented with unusual clinical manifestations, i.e. with prominent regional lymphadenopathy ("bubonic leishmaniasis") and with simultaneously emerged skin and mucosal lesions, respectively. Both patients insufficiently responded to oral treatment with miltefosine; resolution of the lesions was only achieved after a course of intravenous liposomal amphotericin B.

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Authors+Show Affiliations

Eichner S
Hautklinik Mikrobiologisches Institut-Universitätsklinikum Erlangen Wasserturmstraβe 3/5, 91054 Erlangen Germany.
Thoma-Uszynski S
No affiliation info available
Herrgott I
No affiliation info available
Sebald H
No affiliation info available
Debus A
No affiliation info available
Tsianakas A
No affiliation info available
Ehrchen J
No affiliation info available
Harms G
No affiliation info available
Simon M
No affiliation info available
Sunderkötter C
No affiliation info available
Bogdan C
No affiliation info available

MeSH

AdultAgedAmphotericin BAntiprotozoal AgentsHumansLeishmania braziliensisLeishmaniasis, CutaneousMalePhosphorylcholineSouth AmericaTravelYoung Adult

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23557633

Citation

Eichner, Saskia, et al. "Clinical Complexity of Leishmania (Viannia) Braziliensis Infections Amongst Travelers." European Journal of Dermatology : EJD, vol. 23, no. 2, 2013, pp. 218-23.
Eichner S, Thoma-Uszynski S, Herrgott I, et al. Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers. Eur J Dermatol. 2013;23(2):218-23.
Eichner, S., Thoma-Uszynski, S., Herrgott, I., Sebald, H., Debus, A., Tsianakas, A., Ehrchen, J., Harms, G., Simon, M., Sunderkötter, C., & Bogdan, C. (2013). Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers. European Journal of Dermatology : EJD, 23(2), 218-23. https://doi.org/10.1684/ejd.2013.1934
Eichner S, et al. Clinical Complexity of Leishmania (Viannia) Braziliensis Infections Amongst Travelers. Eur J Dermatol. 2013 Apr 1;23(2):218-23. PubMed PMID: 23557633.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical complexity of Leishmania (Viannia) braziliensis infections amongst travelers. AU - Eichner,Saskia, AU - Thoma-Uszynski,Sybille, AU - Herrgott,Ilka, AU - Sebald,Heidi, AU - Debus,Andrea, AU - Tsianakas,Athanasios, AU - Ehrchen,Jan, AU - Harms,Gundel, AU - Simon,Miklos, AU - Sunderkötter,Cord, AU - Bogdan,Christian, PY - 2013/4/6/entrez PY - 2013/4/6/pubmed PY - 2014/2/14/medline KW - Leishmania (V.) braziliensis KW - cutaneous leishmaniasis KW - mucosal leishmaniasis SP - 218 EP - 23 JF - European journal of dermatology : EJD JO - Eur J Dermatol VL - 23 IS - 2 N2 - The protozoan parasite Leishmania (Viannia) braziliensis is one of the main causes of cutaneous and mucocutaneous leishmaniasis in South America. Here, we describe three cases of L. (V.) braziliensis infection which were acquired during travelling in Bolivia, Peru or Paraguay and illustrate the phenotypic heterogeneity and therapeutic complexity of the disease. Two patients presented with unusual clinical manifestations, i.e. with prominent regional lymphadenopathy ("bubonic leishmaniasis") and with simultaneously emerged skin and mucosal lesions, respectively. Both patients insufficiently responded to oral treatment with miltefosine; resolution of the lesions was only achieved after a course of intravenous liposomal amphotericin B. SN - 1952-4013 UR - https://www.unboundmedicine.com/medline/citation/23557633/Clinical_complexity_of_Leishmania__Viannia__braziliensis_infections_amongst_travelers_ L2 - http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ejd.2013.1934 DB - PRIME DP - Unbound Medicine ER -