Tags

Type your tag names separated by a space and hit enter

Arrhythmogenic effect of flecainide toxicity.
Cardiol J. 2013; 20(2):203-5.CJ

Abstract

Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. In overdose cases, flecainide can induce life treating ventricular arrhythmias and cardiogenic shock. We report the case of a 72-year-old woman admitted to our intensive care unit for a regular monomorphic wide complex tachycardia (QRS duration 240 ms, right bundle branch block and superior axis morphology) without apparent P waves. Clinical examination showed slight left congestive heart failure signs without cardiogenic shock. An intravenous bolus of 10 mg adenosine 5'-triphosphate (ATP) was ineffective to stop the tachycardia. The diagnosis of ventricular tachycardia induced by flecainide overdose was considered. 500 mL of intravenous 84‰ sodium bicarbonate was administrated. The patient's QRS narrowed immediately and 12-lead ECG showed sinus rhythm. Blood samples confirmed the flecainide overdose and the clinical status progressively improved.

Authors+Show Affiliations

pycourand@hotmail.com.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

23558880

Citation

Courand, Pierre-Yves Nd, et al. "Arrhythmogenic Effect of Flecainide Toxicity." Cardiology Journal, vol. 20, no. 2, 2013, pp. 203-5.
Courand PY, Sibellas F, Ranc S, et al. Arrhythmogenic effect of flecainide toxicity. Cardiol J. 2013;20(2):203-5.
Courand, P. Y., Sibellas, F., Ranc, S., Mullier, A., Kirkorian, G., & Bonnefoy, E. (2013). Arrhythmogenic effect of flecainide toxicity. Cardiology Journal, 20(2), 203-5. https://doi.org/10.5603/CJ.2013.0035
Courand PY, et al. Arrhythmogenic Effect of Flecainide Toxicity. Cardiol J. 2013;20(2):203-5. PubMed PMID: 23558880.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Arrhythmogenic effect of flecainide toxicity. AU - Courand,Pierre-Yves Nd, AU - Sibellas,Franck, AU - Ranc,Sylvain, AU - Mullier,Audrey, AU - Kirkorian,Gilbert, AU - Bonnefoy,Eric, PY - 2013/04/05/received PY - 2013/04/05/accepted PY - 2013/4/6/entrez PY - 2013/4/6/pubmed PY - 2014/8/13/medline SP - 203 EP - 5 JF - Cardiology journal JO - Cardiol J VL - 20 IS - 2 N2 - Flecainide is a class 1C antiarrhythmic drug especially used for the management of supraventricular arrhythmia. In overdose cases, flecainide can induce life treating ventricular arrhythmias and cardiogenic shock. We report the case of a 72-year-old woman admitted to our intensive care unit for a regular monomorphic wide complex tachycardia (QRS duration 240 ms, right bundle branch block and superior axis morphology) without apparent P waves. Clinical examination showed slight left congestive heart failure signs without cardiogenic shock. An intravenous bolus of 10 mg adenosine 5'-triphosphate (ATP) was ineffective to stop the tachycardia. The diagnosis of ventricular tachycardia induced by flecainide overdose was considered. 500 mL of intravenous 84‰ sodium bicarbonate was administrated. The patient's QRS narrowed immediately and 12-lead ECG showed sinus rhythm. Blood samples confirmed the flecainide overdose and the clinical status progressively improved. SN - 1897-5593 UR - https://www.unboundmedicine.com/medline/citation/23558880/Arrhythmogenic_effect_of_flecainide_toxicity_ L2 - http://czasopisma.viamedica.pl/cj/article/view/33974 DB - PRIME DP - Unbound Medicine ER -