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Effect of iron status on iron absorption in different habitual meals in young south Indian women.

Abstract

BACKGROUND & OBJECTIVES

Iron deficiency (ID) affects a large number of women in India. An inverse relationship exists between iron (Fe) status and Fe absorption. Dietary inhibitory and enhancing factors exert a profound influence on bioavailability of Fe. Although the current recommended dietary allowance (RDA) for Fe is based on 8 per cent bioavailability, it is not clear if this holds good for the usual highly inhibitory Indian diet matrix. This study was aimed to determine Fe absorption from several habitually consumed south Indian food and to evaluate the interaction of Fe status with absorption.

METHODS

Four Fe absorption studies were performed on 60 apparently healthy young women, aged 18-35 years. Based on blood biochemistry, 45 of them were ID and 15 were iron replete (IR). The habitual meals assessed were rice, millet and wheat based meals in the ID subjects and rice based meal alone in the IR subjects. Each subject received the test meal labelled with 3 mg of ⁵⁷Fe and Fe absorption was measured based on erythrocyte incorporation of isotope label 14 days following administration.

RESULTS

Mean fractional Fe absorption from the rice, wheat and millet based meals in the ID subjects were 8.3, 11.2 and 4.6 per cent, respectively. Fe absorption from the rice-based meals was 2.5 per cent in IR subjects.

INTERPRETATION & CONCLUSIONS

Fe absorption is dictated by Fe status from low bioavailability meals. Millet based meals have the lowest bioavailability, while the rice and wheat based meals had moderate to good bioavailability. In millet based meals, it is prudent to consider ways to improve Fe absorption.

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  • Authors+Show Affiliations

    ,

    Division of Nutrition, St. John's Research Institute, St. John's National Academy of Health Sciences, Bangalore, India.

    ,

    Source

    MeSH

    Absorption
    Adult
    Anemia, Iron-Deficiency
    Biological Availability
    Female
    Humans
    India
    Iron
    Oryza
    Panicum
    Triticum
    Young Adult

    Pub Type(s)

    Journal Article

    Language

    eng

    PubMed ID

    23563376

    Citation

    Kalasuramath, Suneeta, et al. "Effect of Iron Status On Iron Absorption in Different Habitual Meals in Young South Indian Women." The Indian Journal of Medical Research, vol. 137, no. 2, 2013, pp. 324-30.
    Kalasuramath S, Kurpad AV, Thankachan P. Effect of iron status on iron absorption in different habitual meals in young south Indian women. Indian J Med Res. 2013;137(2):324-30.
    Kalasuramath, S., Kurpad, A. V., & Thankachan, P. (2013). Effect of iron status on iron absorption in different habitual meals in young south Indian women. The Indian Journal of Medical Research, 137(2), pp. 324-30.
    Kalasuramath S, Kurpad AV, Thankachan P. Effect of Iron Status On Iron Absorption in Different Habitual Meals in Young South Indian Women. Indian J Med Res. 2013;137(2):324-30. PubMed PMID: 23563376.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Effect of iron status on iron absorption in different habitual meals in young south Indian women. AU - Kalasuramath,Suneeta, AU - Kurpad,Anura V, AU - Thankachan,Prashanth, PY - 2013/4/9/entrez PY - 2013/4/9/pubmed PY - 2014/1/1/medline SP - 324 EP - 30 JF - The Indian journal of medical research JO - Indian J. Med. Res. VL - 137 IS - 2 N2 - BACKGROUND & OBJECTIVES: Iron deficiency (ID) affects a large number of women in India. An inverse relationship exists between iron (Fe) status and Fe absorption. Dietary inhibitory and enhancing factors exert a profound influence on bioavailability of Fe. Although the current recommended dietary allowance (RDA) for Fe is based on 8 per cent bioavailability, it is not clear if this holds good for the usual highly inhibitory Indian diet matrix. This study was aimed to determine Fe absorption from several habitually consumed south Indian food and to evaluate the interaction of Fe status with absorption. METHODS: Four Fe absorption studies were performed on 60 apparently healthy young women, aged 18-35 years. Based on blood biochemistry, 45 of them were ID and 15 were iron replete (IR). The habitual meals assessed were rice, millet and wheat based meals in the ID subjects and rice based meal alone in the IR subjects. Each subject received the test meal labelled with 3 mg of ⁵⁷Fe and Fe absorption was measured based on erythrocyte incorporation of isotope label 14 days following administration. RESULTS: Mean fractional Fe absorption from the rice, wheat and millet based meals in the ID subjects were 8.3, 11.2 and 4.6 per cent, respectively. Fe absorption from the rice-based meals was 2.5 per cent in IR subjects. INTERPRETATION & CONCLUSIONS: Fe absorption is dictated by Fe status from low bioavailability meals. Millet based meals have the lowest bioavailability, while the rice and wheat based meals had moderate to good bioavailability. In millet based meals, it is prudent to consider ways to improve Fe absorption. SN - 0971-5916 UR - https://www.unboundmedicine.com/medline/citation/23563376/Effect_of_iron_status_on_iron_absorption_in_different_habitual_meals_in_young_south_Indian_women_ L2 - http://www.ijmr.org.in/article.asp?issn=0971-5916;year=2013;volume=137;issue=2;spage=324;epage=330;aulast=Kalasuramath DB - PRIME DP - Unbound Medicine ER -