TY - JOUR T1 - Antifungal activity of Aegle marmelos (L.) Correa (Rutaceae) leaf extract on dermatophytes. AU - Balakumar,S, AU - Rajan,S, AU - Thirunalasundari,T, AU - Jeeva,S, PY - 2011/02/20/received PY - 2011/03/19/revised PY - 2011/04/10/accepted PY - 2013/4/10/entrez PY - 2011/8/1/pubmed PY - 2011/8/1/medline KW - Aegle marmelos KW - Antifungal activity KW - Dermatophytes KW - Dermatophytosis SP - 309 EP - 12 JF - Asian Pacific journal of tropical biomedicine JO - Asian Pac J Trop Biomed VL - 1 IS - 4 N2 - OBJECTIVE: To evaluate the in vitro antifungal activity of Aegle marmelos leaf extracts and fractions on the clinical isolates of dermatophytic fungi like Trichophyton mentagrophytes, Trichophyton rubrum, Microsporum canis, Microsporum gypseum and Epidermophyton floccosum. METHODS: The minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) of various extracts and fractions of the leaves of Aegle marmelos were measured using method of National Committee for Clinical Laboratory Standards (NCCLS). RESULTS: Aegle marmelos leaf extracts and fractions were found to have fungicidal activity against various clinical isolates of dermatophytic fungi. The MIC and MFC was found to be high in water and ethyl alcohol extracts and methanol fractions (200µg/mL) against dermatophytic fungi studied. CONCLUSIONS: Aegle marmelos leaf extracts significantly inhibites the growth of all dermatophytic fungi studied. If this activity is confirmed by in vivo studies and if the compound is isolated and identified, it could be a remedy for dermatophytosis. SN - 2221-1691 UR - https://www.unboundmedicine.com/medline/citation/23569781/Antifungal_activity_of_Aegle_marmelos__L___Correa__Rutaceae__leaf_extract_on_dermatophytes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/apjtb-01-04-309 DB - PRIME DP - Unbound Medicine ER -