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Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens.
Asian Pac J Trop Biomed. 2012 Aug; 2(8):597-601.AP

Abstract

OBJECTIVE

To evaluate the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection.

METHODS

The cloves of garlic and rhizomes of ginger were extracted with 95% (v/v) ethanol. The ethanolic extracts were subjected to antibacterial sensitivity test against clinical pathogens.

RESULTS

Anti-bacterial potentials of the extracts of two crude garlic cloves and ginger rhizomes were tested against five gram negative and two gram positive multi-drug resistant bacteria isolates. All the bacterial isolates were susceptible to crude extracts of both plants extracts. Except Enterobacter sp. and Klebsiella sp., all other isolates were susceptible when subjected to ethanolic extracts of garlic and ginger. The highest inhibition zone was observed with garlic (19.45 mm) against Pseudomonas aeruginosa (P. aeruginosa). The minimal inhibitory concentration was as low as 67.00 µg/mL against P. aeruginosa.

CONCLUSIONS

Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug resistant microbial diseases and further evaluation is necessary.

Authors+Show Affiliations

Department of Microbiology, K.S. Rangasamy College of Arts and Science, Tiruchengode-637 215, Tamil Nadu, India ; Addiriyah Chair for Environmental Studies, Department of Botany and Microbiology, College of Science, King Saud University, Riyadh - 11541, Kingdom of Saudi Arabia.No affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23569978

Citation

Karuppiah, Ponmurugan, and Shyamkumar Rajaram. "Antibacterial Effect of Allium Sativum Cloves and Zingiber Officinale Rhizomes Against Multiple-drug Resistant Clinical Pathogens." Asian Pacific Journal of Tropical Biomedicine, vol. 2, no. 8, 2012, pp. 597-601.
Karuppiah P, Rajaram S. Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens. Asian Pac J Trop Biomed. 2012;2(8):597-601.
Karuppiah, P., & Rajaram, S. (2012). Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens. Asian Pacific Journal of Tropical Biomedicine, 2(8), 597-601. https://doi.org/10.1016/S2221-1691(12)60104-X
Karuppiah P, Rajaram S. Antibacterial Effect of Allium Sativum Cloves and Zingiber Officinale Rhizomes Against Multiple-drug Resistant Clinical Pathogens. Asian Pac J Trop Biomed. 2012;2(8):597-601. PubMed PMID: 23569978.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antibacterial effect of Allium sativum cloves and Zingiber officinale rhizomes against multiple-drug resistant clinical pathogens. AU - Karuppiah,Ponmurugan, AU - Rajaram,Shyamkumar, PY - 2011/11/11/received PY - 2011/11/29/revised PY - 2012/02/02/accepted PY - 2013/4/10/entrez PY - 2013/4/10/pubmed PY - 2013/4/10/medline KW - Allium sativum KW - Antibacterial activity KW - Garlic KW - Ginger KW - Multi-drug resistant KW - Multiple antibiotic resistance KW - Zingiber officinale SP - 597 EP - 601 JF - Asian Pacific journal of tropical biomedicine JO - Asian Pac J Trop Biomed VL - 2 IS - 8 N2 - OBJECTIVE: To evaluate the antibacterial properties of Allium sativum (garlic) cloves and Zingiber officinale (ginger) rhizomes against multi-drug resistant clinical pathogens causing nosocomial infection. METHODS: The cloves of garlic and rhizomes of ginger were extracted with 95% (v/v) ethanol. The ethanolic extracts were subjected to antibacterial sensitivity test against clinical pathogens. RESULTS: Anti-bacterial potentials of the extracts of two crude garlic cloves and ginger rhizomes were tested against five gram negative and two gram positive multi-drug resistant bacteria isolates. All the bacterial isolates were susceptible to crude extracts of both plants extracts. Except Enterobacter sp. and Klebsiella sp., all other isolates were susceptible when subjected to ethanolic extracts of garlic and ginger. The highest inhibition zone was observed with garlic (19.45 mm) against Pseudomonas aeruginosa (P. aeruginosa). The minimal inhibitory concentration was as low as 67.00 µg/mL against P. aeruginosa. CONCLUSIONS: Natural spices of garlic and ginger possess effective anti-bacterial activity against multi-drug clinical pathogens and can be used for prevention of drug resistant microbial diseases and further evaluation is necessary. SN - 2221-1691 UR - https://www.unboundmedicine.com/medline/citation/23569978/Antibacterial_effect_of_Allium_sativum_cloves_and_Zingiber_officinale_rhizomes_against_multiple_drug_resistant_clinical_pathogens_ L2 - https://linkinghub.elsevier.com/retrieve/pii/apjtb-02-08-597 DB - PRIME DP - Unbound Medicine ER -