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Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages.
Chem Biodivers. 2013 Apr; 10(4):621-7.CB

Abstract

The chemical compositions and antimicrobial activities of essential oils from the leaves, stems, capitula, and cypselas of Chromolaena laevigata were evaluated at two different phenological stages, flowering and fruiting. Thirty-eight compounds were identified in the crude oils by GC/MS. The sesquiterpene laevigatin was the major constituent of the leaf, capitulum, and cypsela oils, while the sesquiterpene spathulenol was the main component in the stem oils. The antimicrobial activities of the oils were evaluated against Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Stem oil obtained from Chromolaena laevigata during the fruiting stage generally showed the highest activity with minimum inhibitory concentration (MIC) values of 62.5 μg/ml against Candida albicans and S. aureus, and 500 μg/ml against P. aeruginosa and E. coli. Pure laevigatin exhibited MIC values of 500 and 125 μg/ml against C. albicans and S. aureus, respectively, indicating that this constituent could be responsible, at least in part, for the antimicrobial activities detected in the crude oils. More studies concerning the biological activities of isolated derivatives are required to improve our knowledge of the antimicrobial potential of volatile compounds present in native plants.

Authors+Show Affiliations

Instituto de Botânica, Secretaria do Meio Ambiente, Av. Miguel Stéfano 3687, Água Funda, 04301-902, São Paulo, SP, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23576348

Citation

Murakami, Cynthia, et al. "Chemical Composition and Antimicrobial Activity of Essential Oils From Chromolaena Laevigata During Flowering and Fruiting Stages." Chemistry & Biodiversity, vol. 10, no. 4, 2013, pp. 621-7.
Murakami C, Lago JH, Perazzo FF, et al. Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages. Chem Biodivers. 2013;10(4):621-7.
Murakami, C., Lago, J. H., Perazzo, F. F., Ferreira, K. S., Lima, M. E., Moreno, P. R., & Young, M. C. (2013). Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages. Chemistry & Biodiversity, 10(4), 621-7. https://doi.org/10.1002/cbdv.201200025
Murakami C, et al. Chemical Composition and Antimicrobial Activity of Essential Oils From Chromolaena Laevigata During Flowering and Fruiting Stages. Chem Biodivers. 2013;10(4):621-7. PubMed PMID: 23576348.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages. AU - Murakami,Cynthia, AU - Lago,João H G, AU - Perazzo,Fábio F, AU - Ferreira,Karen S, AU - Lima,Marcos E L, AU - Moreno,Paulo R H, AU - Young,Maria C M, PY - 2012/01/23/received PY - 2013/4/12/entrez PY - 2013/4/12/pubmed PY - 2013/10/18/medline SP - 621 EP - 7 JF - Chemistry & biodiversity JO - Chem Biodivers VL - 10 IS - 4 N2 - The chemical compositions and antimicrobial activities of essential oils from the leaves, stems, capitula, and cypselas of Chromolaena laevigata were evaluated at two different phenological stages, flowering and fruiting. Thirty-eight compounds were identified in the crude oils by GC/MS. The sesquiterpene laevigatin was the major constituent of the leaf, capitulum, and cypsela oils, while the sesquiterpene spathulenol was the main component in the stem oils. The antimicrobial activities of the oils were evaluated against Candida albicans, Staphylococcus aureus, Pseudomonas aeruginosa, and Escherichia coli. Stem oil obtained from Chromolaena laevigata during the fruiting stage generally showed the highest activity with minimum inhibitory concentration (MIC) values of 62.5 μg/ml against Candida albicans and S. aureus, and 500 μg/ml against P. aeruginosa and E. coli. Pure laevigatin exhibited MIC values of 500 and 125 μg/ml against C. albicans and S. aureus, respectively, indicating that this constituent could be responsible, at least in part, for the antimicrobial activities detected in the crude oils. More studies concerning the biological activities of isolated derivatives are required to improve our knowledge of the antimicrobial potential of volatile compounds present in native plants. SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/23576348/Chemical_composition_and_antimicrobial_activity_of_essential_oils_from_Chromolaena_laevigata_during_flowering_and_fruiting_stages_ L2 - https://doi.org/10.1002/cbdv.201200025 DB - PRIME DP - Unbound Medicine ER -