Tags

Type your tag names separated by a space and hit enter

Influence of Mediterranean diet on asthma in children: a systematic review and meta-analysis.
Pediatr Allergy Immunol. 2013 Jun; 24(4):330-8.PA

Abstract

BACKGROUND

There is epidemiological evidence that Mediterranean diet exposure is associated with lower asthma prevalence in children. We aimed to summarize the available data and to know whether the Mediterranean setting modifies this association.

METHODS

The literature search, up to May 2012, was on epidemiological studies in the general population of children assessing whether adherence to Mediterranean diet (measured as a score) was associated with the prevalence of 'current wheeze'; 'current severe wheeze'; or 'asthma ever'. Odds ratios (OR) of the eight included studies compared the highest tertile of the score with the lowest. Random-effects meta-analyses for the whole group of studies and stratified by Mediterranean setting (centers <100 Km from the Mediterranean coast) were performed. Differences between strata were assessed using the Q test.

RESULTS

For 'current wheeze', there was a negative significant association with the highest tertile of Mediterranean diet score (OR 0.85, 95% CI 0.75-0.98; p = 0.02), driven by Mediterranean centers (0.79, 0.66-0.94, p = 0.009), although the difference with the non-Mediterranean centers (0.91, 0.78-1.05, p = 0.18) was not significant. The results for 'current severe wheeze' were as follows: 0.82, 0.55-1.22, p = 0.330 (all); 0.66, 0.48-0.90, p = 0.008 (Mediterranean); and 0.99, 0.79-1.25, p = 0.95 (non-Mediterranean); with the difference between regions being significant. For 'asthma ever', the associations were as follows: 0.86, 0.78-0.95, p = 0.004 (all); 0.86, 0.74-1.01, p = 0.06 (Mediterranean); 0.86, 0.75-0.98; p = 0.027 (non-Mediterranean); with the difference between regions being negligible.

CONCLUSIONS

Adherence to the Mediterranean diet tended to be associated with lower occurrence of the three respiratory outcomes. For current and current severe wheeze, the association was mainly driven by the results in Mediterranean populations.

Authors+Show Affiliations

Pediatric Respiratory and Allergy Units, 'Virgen de la Arrixaca' University Children's Hospital, University of Murcia, Murcia, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Meta-Analysis
Review
Systematic Review

Language

eng

PubMed ID

23578354

Citation

Garcia-Marcos, L, et al. "Influence of Mediterranean Diet On Asthma in Children: a Systematic Review and Meta-analysis." Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, vol. 24, no. 4, 2013, pp. 330-8.
Garcia-Marcos L, Castro-Rodriguez JA, Weinmayr G, et al. Influence of Mediterranean diet on asthma in children: a systematic review and meta-analysis. Pediatr Allergy Immunol. 2013;24(4):330-8.
Garcia-Marcos, L., Castro-Rodriguez, J. A., Weinmayr, G., Panagiotakos, D. B., Priftis, K. N., & Nagel, G. (2013). Influence of Mediterranean diet on asthma in children: a systematic review and meta-analysis. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 24(4), 330-8. https://doi.org/10.1111/pai.12071
Garcia-Marcos L, et al. Influence of Mediterranean Diet On Asthma in Children: a Systematic Review and Meta-analysis. Pediatr Allergy Immunol. 2013;24(4):330-8. PubMed PMID: 23578354.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of Mediterranean diet on asthma in children: a systematic review and meta-analysis. AU - Garcia-Marcos,L, AU - Castro-Rodriguez,J A, AU - Weinmayr,G, AU - Panagiotakos,D B, AU - Priftis,K N, AU - Nagel,G, Y1 - 2013/04/11/ PY - 2013/02/20/accepted PY - 2013/4/13/entrez PY - 2013/4/13/pubmed PY - 2014/1/10/medline SP - 330 EP - 8 JF - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JO - Pediatr Allergy Immunol VL - 24 IS - 4 N2 - BACKGROUND: There is epidemiological evidence that Mediterranean diet exposure is associated with lower asthma prevalence in children. We aimed to summarize the available data and to know whether the Mediterranean setting modifies this association. METHODS: The literature search, up to May 2012, was on epidemiological studies in the general population of children assessing whether adherence to Mediterranean diet (measured as a score) was associated with the prevalence of 'current wheeze'; 'current severe wheeze'; or 'asthma ever'. Odds ratios (OR) of the eight included studies compared the highest tertile of the score with the lowest. Random-effects meta-analyses for the whole group of studies and stratified by Mediterranean setting (centers <100 Km from the Mediterranean coast) were performed. Differences between strata were assessed using the Q test. RESULTS: For 'current wheeze', there was a negative significant association with the highest tertile of Mediterranean diet score (OR 0.85, 95% CI 0.75-0.98; p = 0.02), driven by Mediterranean centers (0.79, 0.66-0.94, p = 0.009), although the difference with the non-Mediterranean centers (0.91, 0.78-1.05, p = 0.18) was not significant. The results for 'current severe wheeze' were as follows: 0.82, 0.55-1.22, p = 0.330 (all); 0.66, 0.48-0.90, p = 0.008 (Mediterranean); and 0.99, 0.79-1.25, p = 0.95 (non-Mediterranean); with the difference between regions being significant. For 'asthma ever', the associations were as follows: 0.86, 0.78-0.95, p = 0.004 (all); 0.86, 0.74-1.01, p = 0.06 (Mediterranean); 0.86, 0.75-0.98; p = 0.027 (non-Mediterranean); with the difference between regions being negligible. CONCLUSIONS: Adherence to the Mediterranean diet tended to be associated with lower occurrence of the three respiratory outcomes. For current and current severe wheeze, the association was mainly driven by the results in Mediterranean populations. SN - 1399-3038 UR - https://www.unboundmedicine.com/medline/citation/23578354/Influence_of_Mediterranean_diet_on_asthma_in_children:_a_systematic_review_and_meta_analysis_ L2 - https://doi.org/10.1111/pai.12071 DB - PRIME DP - Unbound Medicine ER -