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Impact on iron status of introducing cow's milk in the second six months of life.
J Pediatr Gastroenterol Nutr. 1990 May; 10(4):462-7.JP

Abstract

To determine the impact on iron status of introducing cow's milk (CM) into the diet during the second 6 months of life, nutrient intake was assessed and iron status measured in 100 infants. Nutrient intake for 40 of the 45 infants, age 8 to 13 months, fed CM as the primary beverage for at least 3 months prior to the study and for 45 of 55 infants the same age fed a milk-based infant formula (FF) as the primary beverage for at least 3 months were assessed. All infants in the study were healthy, and the majority were taking no medications or supplements other than vitamins or fluoride for 3 weeks prior to the assessment. Blood drawn by peripheral venipuncture was analyzed by Coulter Counter for complete blood count; plasma albumin, iron, ferritin, transferrin saturation, and total iron-binding capacity were measured in all infants. CM-fed infants had significantly lower mean iron and vitamin C intakes, plasma albumin, transferrin saturation, and ferritin than did FF infants. The frequency of low plasma iron, low transferrin saturation, and low plasma ferritin was significantly greater in CM-fed than in FF infants. The percentage of subjects with three or more abnormal iron indices was more than twice as great in CM-fed infants (58%) as in FF infants (23%). Feeding infants iron-fortified formula to 12 months of age appears to deter iron deficiency.

Authors+Show Affiliations

Department of Nutrition and Food Science, Florida State University, Tallahassee.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2358978

Citation

Penrod, J C., et al. "Impact On Iron Status of Introducing Cow's Milk in the Second Six Months of Life." Journal of Pediatric Gastroenterology and Nutrition, vol. 10, no. 4, 1990, pp. 462-7.
Penrod JC, Anderson K, Acosta PB. Impact on iron status of introducing cow's milk in the second six months of life. J Pediatr Gastroenterol Nutr. 1990;10(4):462-7.
Penrod, J. C., Anderson, K., & Acosta, P. B. (1990). Impact on iron status of introducing cow's milk in the second six months of life. Journal of Pediatric Gastroenterology and Nutrition, 10(4), 462-7.
Penrod JC, Anderson K, Acosta PB. Impact On Iron Status of Introducing Cow's Milk in the Second Six Months of Life. J Pediatr Gastroenterol Nutr. 1990;10(4):462-7. PubMed PMID: 2358978.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Impact on iron status of introducing cow's milk in the second six months of life. AU - Penrod,J C, AU - Anderson,K, AU - Acosta,P B, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - 462 EP - 7 JF - Journal of pediatric gastroenterology and nutrition JO - J Pediatr Gastroenterol Nutr VL - 10 IS - 4 N2 - To determine the impact on iron status of introducing cow's milk (CM) into the diet during the second 6 months of life, nutrient intake was assessed and iron status measured in 100 infants. Nutrient intake for 40 of the 45 infants, age 8 to 13 months, fed CM as the primary beverage for at least 3 months prior to the study and for 45 of 55 infants the same age fed a milk-based infant formula (FF) as the primary beverage for at least 3 months were assessed. All infants in the study were healthy, and the majority were taking no medications or supplements other than vitamins or fluoride for 3 weeks prior to the assessment. Blood drawn by peripheral venipuncture was analyzed by Coulter Counter for complete blood count; plasma albumin, iron, ferritin, transferrin saturation, and total iron-binding capacity were measured in all infants. CM-fed infants had significantly lower mean iron and vitamin C intakes, plasma albumin, transferrin saturation, and ferritin than did FF infants. The frequency of low plasma iron, low transferrin saturation, and low plasma ferritin was significantly greater in CM-fed than in FF infants. The percentage of subjects with three or more abnormal iron indices was more than twice as great in CM-fed infants (58%) as in FF infants (23%). Feeding infants iron-fortified formula to 12 months of age appears to deter iron deficiency. SN - 0277-2116 UR - https://www.unboundmedicine.com/medline/citation/2358978/Impact_on_iron_status_of_introducing_cow's_milk_in_the_second_six_months_of_life_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=2358978.ui DB - PRIME DP - Unbound Medicine ER -