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Free radical scavenging and total antioxidant capacity of root extracts of Anchomanes difformis Engl. (Araceae).
Acta Pol Pharm. 2013 Jan-Feb; 70(1):115-21.AP

Abstract

Antioxidants activities from plants sources have attracted a wide range of interest across the world in recent times. This is due to growing concern for safe and alternative sources of antioxidants. The free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl radical (DPPH), reducing power assay, total antioxidant capacity of the phosphomolybdenum method and the total phenolics content using the Folin-Ciocalteu reagent were carried out on the acetone, n-butanol and methanol root extracts of Anchomanes difformis. The results of the total phenolics content expressed in mg/100 g of gallic acid equivalent (GAE) showed that the n-butanol extract has significantly (p < 0.05) higher phenolics content (381 +/- 1.13) than the methanol and acetone extracts. All the extracts displayed strong concentration dependent radical scavenging activity. It was also observed that the n-butanol extract showed higher activity of 70.87% and 78.59% at low concentrations of 31.25 microg/mL and 62.5 microg/mL, respectively, than methanol and acetone extracts. The results also showed that the n-butanol extract has strongest reducing ability which is comparable to that of gallic acid at all the concentrations tested. Phytochemical screening on the extracts revealed the presence of flavonoids, saponins, and tannins. The results suggest that n-butanol extract of the plant is very rich in antioxidant compounds worthy of further investigations.

Authors+Show Affiliations

Department of Chemistry, Ahmadu Bello University, Zaria, Nigeria. aliyubabando@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

23610966

Citation

Aliyu, Abubakar B., et al. "Free Radical Scavenging and Total Antioxidant Capacity of Root Extracts of Anchomanes Difformis Engl. (Araceae)." Acta Poloniae Pharmaceutica, vol. 70, no. 1, 2013, pp. 115-21.
Aliyu AB, Ibrahim MA, Musa AM, et al. Free radical scavenging and total antioxidant capacity of root extracts of Anchomanes difformis Engl. (Araceae). Acta Pol Pharm. 2013;70(1):115-21.
Aliyu, A. B., Ibrahim, M. A., Musa, A. M., Musa, A. O., Kiplimo, J. J., & Oyewale, A. O. (2013). Free radical scavenging and total antioxidant capacity of root extracts of Anchomanes difformis Engl. (Araceae). Acta Poloniae Pharmaceutica, 70(1), 115-21.
Aliyu AB, et al. Free Radical Scavenging and Total Antioxidant Capacity of Root Extracts of Anchomanes Difformis Engl. (Araceae). Acta Pol Pharm. 2013;70(1):115-21. PubMed PMID: 23610966.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Free radical scavenging and total antioxidant capacity of root extracts of Anchomanes difformis Engl. (Araceae). AU - Aliyu,Abubakar B, AU - Ibrahim,Mohammed A, AU - Musa,Aliyu M, AU - Musa,Aisha O, AU - Kiplimo,Joyce J, AU - Oyewale,Adebayo O, PY - 2013/4/25/entrez PY - 2013/4/25/pubmed PY - 2013/6/19/medline SP - 115 EP - 21 JF - Acta poloniae pharmaceutica JO - Acta Pol Pharm VL - 70 IS - 1 N2 - Antioxidants activities from plants sources have attracted a wide range of interest across the world in recent times. This is due to growing concern for safe and alternative sources of antioxidants. The free radical scavenging activity using 1,1-diphenyl-2-picrylhydrazyl radical (DPPH), reducing power assay, total antioxidant capacity of the phosphomolybdenum method and the total phenolics content using the Folin-Ciocalteu reagent were carried out on the acetone, n-butanol and methanol root extracts of Anchomanes difformis. The results of the total phenolics content expressed in mg/100 g of gallic acid equivalent (GAE) showed that the n-butanol extract has significantly (p < 0.05) higher phenolics content (381 +/- 1.13) than the methanol and acetone extracts. All the extracts displayed strong concentration dependent radical scavenging activity. It was also observed that the n-butanol extract showed higher activity of 70.87% and 78.59% at low concentrations of 31.25 microg/mL and 62.5 microg/mL, respectively, than methanol and acetone extracts. The results also showed that the n-butanol extract has strongest reducing ability which is comparable to that of gallic acid at all the concentrations tested. Phytochemical screening on the extracts revealed the presence of flavonoids, saponins, and tannins. The results suggest that n-butanol extract of the plant is very rich in antioxidant compounds worthy of further investigations. SN - 0001-6837 UR - https://www.unboundmedicine.com/medline/citation/23610966/Free_radical_scavenging_and_total_antioxidant_capacity_of_root_extracts_of_Anchomanes_difformis_Engl___Araceae__ L2 - http://www.ptfarm.pl/pub/File/Acta_Poloniae/2013/1/115.pdf DB - PRIME DP - Unbound Medicine ER -