Tags

Type your tag names separated by a space and hit enter

Characterization of clade 2.3.2.1 H5N1 highly pathogenic avian influenza viruses isolated from wild birds (mandarin duck and Eurasian eagle owl) in 2010 in Korea.
Viruses. 2013 Apr 23; 5(4):1153-74.V

Abstract

Starting in late November 2010, the H5N1 highly pathogenic avian influenza (HPAI) virus was isolated from many types of wild ducks and raptors and was subsequently isolated from poultry in Korea. We assessed the genetic and pathogenic properties of the HPAI viruses isolated from a fecal sample from a mandarin duck and a dead Eurasian eagle owl, the most affected wild bird species during the 2010/2011 HPAI outbreak in Korea. These viruses have similar genetic backgrounds and exhibited the highest genetic similarity with recent Eurasian clade 2.3.2.1 HPAI viruses. In animal inoculation experiments, regardless of their originating hosts, the two Korean isolates produced highly pathogenic characteristics in chickens, ducks and mice without pre-adaptation. These results raise concerns about veterinary and public health. Surveillance of wild birds could provide a good early warning signal for possible HPAI infection in poultry as well as in humans.

Authors+Show Affiliations

Animal, Plant and Fisheries Quarantine and Inspection Agency, 175 Anyangro, Manangu, Anyang, Gyeonggi 430-757, Republic of Korea. happythomas@korea.krNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23611846

Citation

Choi, Jun-Gu, et al. "Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated From Wild Birds (mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea." Viruses, vol. 5, no. 4, 2013, pp. 1153-74.
Choi JG, Kang HM, Jeon WJ, et al. Characterization of clade 2.3.2.1 H5N1 highly pathogenic avian influenza viruses isolated from wild birds (mandarin duck and Eurasian eagle owl) in 2010 in Korea. Viruses. 2013;5(4):1153-74.
Choi, J. G., Kang, H. M., Jeon, W. J., Choi, K. S., Kim, K. I., Song, B. M., Lee, H. S., Kim, J. H., & Lee, Y. J. (2013). Characterization of clade 2.3.2.1 H5N1 highly pathogenic avian influenza viruses isolated from wild birds (mandarin duck and Eurasian eagle owl) in 2010 in Korea. Viruses, 5(4), 1153-74. https://doi.org/10.3390/v5041153
Choi JG, et al. Characterization of Clade 2.3.2.1 H5N1 Highly Pathogenic Avian Influenza Viruses Isolated From Wild Birds (mandarin Duck and Eurasian Eagle Owl) in 2010 in Korea. Viruses. 2013 Apr 23;5(4):1153-74. PubMed PMID: 23611846.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of clade 2.3.2.1 H5N1 highly pathogenic avian influenza viruses isolated from wild birds (mandarin duck and Eurasian eagle owl) in 2010 in Korea. AU - Choi,Jun-Gu, AU - Kang,Hyun-Mi, AU - Jeon,Woo-Jin, AU - Choi,Kang-Seuk, AU - Kim,Kwang-Il, AU - Song,Byung Min, AU - Lee,Hee-Soo, AU - Kim,Jae-Hong, AU - Lee,Youn-Jeong, Y1 - 2013/04/23/ PY - 2013/03/25/received PY - 2013/04/18/revised PY - 2013/04/20/accepted PY - 2013/4/25/entrez PY - 2013/4/25/pubmed PY - 2013/9/14/medline SP - 1153 EP - 74 JF - Viruses JO - Viruses VL - 5 IS - 4 N2 - Starting in late November 2010, the H5N1 highly pathogenic avian influenza (HPAI) virus was isolated from many types of wild ducks and raptors and was subsequently isolated from poultry in Korea. We assessed the genetic and pathogenic properties of the HPAI viruses isolated from a fecal sample from a mandarin duck and a dead Eurasian eagle owl, the most affected wild bird species during the 2010/2011 HPAI outbreak in Korea. These viruses have similar genetic backgrounds and exhibited the highest genetic similarity with recent Eurasian clade 2.3.2.1 HPAI viruses. In animal inoculation experiments, regardless of their originating hosts, the two Korean isolates produced highly pathogenic characteristics in chickens, ducks and mice without pre-adaptation. These results raise concerns about veterinary and public health. Surveillance of wild birds could provide a good early warning signal for possible HPAI infection in poultry as well as in humans. SN - 1999-4915 UR - https://www.unboundmedicine.com/medline/citation/23611846/Characterization_of_clade_2_3_2_1_H5N1_highly_pathogenic_avian_influenza_viruses_isolated_from_wild_birds__mandarin_duck_and_Eurasian_eagle_owl__in_2010_in_Korea_ L2 - https://www.mdpi.com/resolver?pii=v5041153 DB - PRIME DP - Unbound Medicine ER -