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Image quality of low-dose CCTA in obese patients: impact of high-definition computed tomography and adaptive statistical iterative reconstruction.
Int J Cardiovasc Imaging. 2013 Oct; 29(7):1565-74.IJ

Abstract

The accuracy of coronary computed tomography angiography (CCTA) in obese persons is compromised by increased image noise. We investigated CCTA image quality acquired on a high-definition 64-slice CT scanner using modern adaptive statistical iterative reconstruction (ASIR). Seventy overweight and obese patients (24 males; mean age 57 years, mean body mass index 33 kg/m(2)) were studied with clinically-indicated contrast enhanced CCTA. Thirty-five patients underwent a standard definition protocol with filtered backprojection reconstruction (SD-FBP) while 35 patients matched for gender, age, body mass index and coronary artery calcifications underwent a novel high definition protocol with ASIR (HD-ASIR). Segment by segment image quality was assessed using a four-point scale (1 = excellent, 2 = good, 3 = moderate, 4 = non-diagnostic) and revealed better scores for HD-ASIR compared to SD-FBP (1.5 ± 0.43 vs. 1.8 ± 0.48; p < 0.05). The smallest detectable vessel diameter was also improved, 1.0 ± 0.5 mm for HD-ASIR as compared to 1.4 ± 0.4 mm for SD-FBP (p < 0.001). Average vessel attenuation was higher for HD-ASIR (388.3 ± 109.6 versus 350.6 ± 90.3 Hounsfield Units, HU; p < 0.05), while image noise, signal-to-noise ratio and contrast-to noise ratio did not differ significantly between reconstruction protocols (p = NS). The estimated effective radiation doses were similar, 2.3 ± 0.1 and 2.5 ± 0.1 mSv (HD-ASIR vs. SD-ASIR respectively). Compared to a standard definition backprojection protocol (SD-FBP), a newer high definition scan protocol in combination with ASIR (HD-ASIR) incrementally improved image quality and visualization of distal coronary artery segments in overweight and obese individuals, without increasing image noise and radiation dose.

Authors+Show Affiliations

Department of Radiology, Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, NUK C 42, 8091, Zurich, Switzerland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23624958

Citation

Gebhard, Cathérine, et al. "Image Quality of Low-dose CCTA in Obese Patients: Impact of High-definition Computed Tomography and Adaptive Statistical Iterative Reconstruction." The International Journal of Cardiovascular Imaging, vol. 29, no. 7, 2013, pp. 1565-74.
Gebhard C, Fuchs TA, Fiechter M, et al. Image quality of low-dose CCTA in obese patients: impact of high-definition computed tomography and adaptive statistical iterative reconstruction. Int J Cardiovasc Imaging. 2013;29(7):1565-74.
Gebhard, C., Fuchs, T. A., Fiechter, M., Stehli, J., Stähli, B. E., Gaemperli, O., & Kaufmann, P. A. (2013). Image quality of low-dose CCTA in obese patients: impact of high-definition computed tomography and adaptive statistical iterative reconstruction. The International Journal of Cardiovascular Imaging, 29(7), 1565-74. https://doi.org/10.1007/s10554-013-0228-4
Gebhard C, et al. Image Quality of Low-dose CCTA in Obese Patients: Impact of High-definition Computed Tomography and Adaptive Statistical Iterative Reconstruction. Int J Cardiovasc Imaging. 2013;29(7):1565-74. PubMed PMID: 23624958.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Image quality of low-dose CCTA in obese patients: impact of high-definition computed tomography and adaptive statistical iterative reconstruction. AU - Gebhard,Cathérine, AU - Fuchs,Tobias A, AU - Fiechter,Michael, AU - Stehli,Julia, AU - Stähli,Barbara E, AU - Gaemperli,Oliver, AU - Kaufmann,Philipp A, Y1 - 2013/04/28/ PY - 2013/01/21/received PY - 2013/04/19/accepted PY - 2013/4/30/entrez PY - 2013/4/30/pubmed PY - 2014/5/28/medline SP - 1565 EP - 74 JF - The international journal of cardiovascular imaging JO - Int J Cardiovasc Imaging VL - 29 IS - 7 N2 - The accuracy of coronary computed tomography angiography (CCTA) in obese persons is compromised by increased image noise. We investigated CCTA image quality acquired on a high-definition 64-slice CT scanner using modern adaptive statistical iterative reconstruction (ASIR). Seventy overweight and obese patients (24 males; mean age 57 years, mean body mass index 33 kg/m(2)) were studied with clinically-indicated contrast enhanced CCTA. Thirty-five patients underwent a standard definition protocol with filtered backprojection reconstruction (SD-FBP) while 35 patients matched for gender, age, body mass index and coronary artery calcifications underwent a novel high definition protocol with ASIR (HD-ASIR). Segment by segment image quality was assessed using a four-point scale (1 = excellent, 2 = good, 3 = moderate, 4 = non-diagnostic) and revealed better scores for HD-ASIR compared to SD-FBP (1.5 ± 0.43 vs. 1.8 ± 0.48; p < 0.05). The smallest detectable vessel diameter was also improved, 1.0 ± 0.5 mm for HD-ASIR as compared to 1.4 ± 0.4 mm for SD-FBP (p < 0.001). Average vessel attenuation was higher for HD-ASIR (388.3 ± 109.6 versus 350.6 ± 90.3 Hounsfield Units, HU; p < 0.05), while image noise, signal-to-noise ratio and contrast-to noise ratio did not differ significantly between reconstruction protocols (p = NS). The estimated effective radiation doses were similar, 2.3 ± 0.1 and 2.5 ± 0.1 mSv (HD-ASIR vs. SD-ASIR respectively). Compared to a standard definition backprojection protocol (SD-FBP), a newer high definition scan protocol in combination with ASIR (HD-ASIR) incrementally improved image quality and visualization of distal coronary artery segments in overweight and obese individuals, without increasing image noise and radiation dose. SN - 1875-8312 UR - https://www.unboundmedicine.com/medline/citation/23624958/Image_quality_of_low_dose_CCTA_in_obese_patients:_impact_of_high_definition_computed_tomography_and_adaptive_statistical_iterative_reconstruction_ L2 - https://doi.org/10.1007/s10554-013-0228-4 DB - PRIME DP - Unbound Medicine ER -