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Biological activities and chemical composition of the stems and roots of Helichrysum oligocephalum DC grown in Iran.
Pak J Pharm Sci. 2013 May; 26(3):599-604.PJ

Abstract

Helichrysum has long been used medicinally, proving to be beneficial in treatment of acne, asthma, bronchitis and circulatory problems, and lymphatic system diseases. The objective of this research was to study the antioxidant and antibacterial activities and chemical composition of the compounds derived from the stems and roots of cultivated H. oligocephalum using gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS). The primary components found in the stem oil were ortho-vanillin (51.0%) and carvacrol (16.0%), and those found in the root oil were 1,8-cineole (30.6%) and isobornyl acetate (13.9%). Stem and root oils of H. oligocephalum demonstrated antibacterial activity, particularly in relation to Gram-positive bacteria. In a β-carotene/linoleic acid bleaching assay, the root oil of H. oligocephalum demonstrated an antioxidant effect. Antioxidant capacity measured with 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was 1205.0 for the stem oil and 722.8 μg/ml for the root oil.

Authors+Show Affiliations

Department of Chemical Engineering, North Tehran Branch, Islamic Azad University, Tehran, Iran. akbaresmaeili@yahoo.com

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23625436

Citation

Esmaeili, Akbar. "Biological Activities and Chemical Composition of the Stems and Roots of Helichrysum Oligocephalum DC Grown in Iran." Pakistan Journal of Pharmaceutical Sciences, vol. 26, no. 3, 2013, pp. 599-604.
Esmaeili A. Biological activities and chemical composition of the stems and roots of Helichrysum oligocephalum DC grown in Iran. Pak J Pharm Sci. 2013;26(3):599-604.
Esmaeili, A. (2013). Biological activities and chemical composition of the stems and roots of Helichrysum oligocephalum DC grown in Iran. Pakistan Journal of Pharmaceutical Sciences, 26(3), 599-604.
Esmaeili A. Biological Activities and Chemical Composition of the Stems and Roots of Helichrysum Oligocephalum DC Grown in Iran. Pak J Pharm Sci. 2013;26(3):599-604. PubMed PMID: 23625436.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Biological activities and chemical composition of the stems and roots of Helichrysum oligocephalum DC grown in Iran. A1 - Esmaeili,Akbar, PY - 2013/4/30/entrez PY - 2013/4/30/pubmed PY - 2013/8/2/medline SP - 599 EP - 604 JF - Pakistan journal of pharmaceutical sciences JO - Pak J Pharm Sci VL - 26 IS - 3 N2 - Helichrysum has long been used medicinally, proving to be beneficial in treatment of acne, asthma, bronchitis and circulatory problems, and lymphatic system diseases. The objective of this research was to study the antioxidant and antibacterial activities and chemical composition of the compounds derived from the stems and roots of cultivated H. oligocephalum using gas chromatography (GC) and gas chromatography-mass spectroscopy (GC-MS). The primary components found in the stem oil were ortho-vanillin (51.0%) and carvacrol (16.0%), and those found in the root oil were 1,8-cineole (30.6%) and isobornyl acetate (13.9%). Stem and root oils of H. oligocephalum demonstrated antibacterial activity, particularly in relation to Gram-positive bacteria. In a β-carotene/linoleic acid bleaching assay, the root oil of H. oligocephalum demonstrated an antioxidant effect. Antioxidant capacity measured with 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay was 1205.0 for the stem oil and 722.8 μg/ml for the root oil. SN - 1011-601X UR - https://www.unboundmedicine.com/medline/citation/23625436/Biological_activities_and_chemical_composition_of_the_stems_and_roots_of_Helichrysum_oligocephalum_DC_grown_in_Iran_ DB - PRIME DP - Unbound Medicine ER -