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Acute alcohol intoxication characteristics in children.
Alcohol Alcohol. 2013 Jul-Aug; 48(4):390-5.AA

Abstract

AIMS

To describe clinical, mental and physical signs in children with different severity acute alcohol intoxication (AAI) determined either by serum alcohol concentration (SAC) or by blood alcohol concentration (BAC) to study the diagnostic performance characteristics of clinical assessment and to establish the ratio of SAC:BAC in children.

METHODS

Data were analysed from 256 children aged 8.4-17.9 years who were hospitalized at Estonia's two children's hospitals over a 3-year period. In each case, the on-call paediatrician completed a special form about the clinical, mental (consciousness, balance and speech) and physical (muscle tone, blood pressure, pulse and body temperature) signs of AAI. Blood samples were drawn for measurements of SAC and BAC. Diagnostic performance characteristics (sensitivity, specificity, efficiency) of the clinical assessments and the SAC:BAC ratio were calculated.

RESULTS

The most correctly described signs in children in different SAC groups were consciousness (rs = 0.16) and speech (rs = 0.13) (P < 0.0001). The severity of alteration of consciousness and degrees of disturbance in balance and speech were positively correlated with SAC (P < 0.001). The clinical judgment matched better with AAI determined by SAC rather than by BAC with the mean efficiency. The mean ratio between SAC and BAC was 1.19 ± 0.13 (P < 0.001) in children.

CONCLUSION

The level of consciousness is the leading sign in the clinical evaluation of children with AAI and correlates well with SAC. The severity of AAI judged by clinical assessment matched better with AAI severity stages determined by SAC than by BAC. For legal cases where BAC is required, the SAC:BAC ratio of 1.19:1 should be used in children regardless of their gender or age.

Authors+Show Affiliations

Department of Pathological Anatomy and Forensic Medicine, University of Tartu, Biomedicum, Ravila 19, Tartu, Estonia. mailis.tonisson@ut.eeNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23632804

Citation

Tõnisson, Mailis, et al. "Acute Alcohol Intoxication Characteristics in Children." Alcohol and Alcoholism (Oxford, Oxfordshire), vol. 48, no. 4, 2013, pp. 390-5.
Tõnisson M, Tillmann V, Kuudeberg A, et al. Acute alcohol intoxication characteristics in children. Alcohol Alcohol. 2013;48(4):390-5.
Tõnisson, M., Tillmann, V., Kuudeberg, A., Lepik, D., & Väli, M. (2013). Acute alcohol intoxication characteristics in children. Alcohol and Alcoholism (Oxford, Oxfordshire), 48(4), 390-5. https://doi.org/10.1093/alcalc/agt036
Tõnisson M, et al. Acute Alcohol Intoxication Characteristics in Children. Alcohol Alcohol. 2013;48(4):390-5. PubMed PMID: 23632804.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute alcohol intoxication characteristics in children. AU - Tõnisson,Mailis, AU - Tillmann,Vallo, AU - Kuudeberg,Anne, AU - Lepik,Delia, AU - Väli,Marika, Y1 - 2013/04/30/ PY - 2013/5/2/entrez PY - 2013/5/2/pubmed PY - 2014/1/17/medline SP - 390 EP - 5 JF - Alcohol and alcoholism (Oxford, Oxfordshire) JO - Alcohol Alcohol. VL - 48 IS - 4 N2 - AIMS: To describe clinical, mental and physical signs in children with different severity acute alcohol intoxication (AAI) determined either by serum alcohol concentration (SAC) or by blood alcohol concentration (BAC) to study the diagnostic performance characteristics of clinical assessment and to establish the ratio of SAC:BAC in children. METHODS: Data were analysed from 256 children aged 8.4-17.9 years who were hospitalized at Estonia's two children's hospitals over a 3-year period. In each case, the on-call paediatrician completed a special form about the clinical, mental (consciousness, balance and speech) and physical (muscle tone, blood pressure, pulse and body temperature) signs of AAI. Blood samples were drawn for measurements of SAC and BAC. Diagnostic performance characteristics (sensitivity, specificity, efficiency) of the clinical assessments and the SAC:BAC ratio were calculated. RESULTS: The most correctly described signs in children in different SAC groups were consciousness (rs = 0.16) and speech (rs = 0.13) (P < 0.0001). The severity of alteration of consciousness and degrees of disturbance in balance and speech were positively correlated with SAC (P < 0.001). The clinical judgment matched better with AAI determined by SAC rather than by BAC with the mean efficiency. The mean ratio between SAC and BAC was 1.19 ± 0.13 (P < 0.001) in children. CONCLUSION: The level of consciousness is the leading sign in the clinical evaluation of children with AAI and correlates well with SAC. The severity of AAI judged by clinical assessment matched better with AAI severity stages determined by SAC than by BAC. For legal cases where BAC is required, the SAC:BAC ratio of 1.19:1 should be used in children regardless of their gender or age. SN - 1464-3502 UR - https://www.unboundmedicine.com/medline/citation/23632804/Acute_alcohol_intoxication_characteristics_in_children_ L2 - https://academic.oup.com/alcalc/article-lookup/doi/10.1093/alcalc/agt036 DB - PRIME DP - Unbound Medicine ER -