Tags

Type your tag names separated by a space and hit enter

The value of combining autofluorescence and optical coherence tomography in predicting the visual prognosis of sealed macular holes.
Am J Ophthalmol. 2013 Jul; 156(1):149-156.e1.AJ

Abstract

PURPOSE

To investigate the autofluorescence patterns of sealed macular holes and determine the correlations of the postoperative changes in spectral-domain optical coherence tomography and fundus autofluorescence (FAF) with the best-corrected visual acuity (BCVA) of patients with sealed idiopathic macular holes.

DESIGN

Retrospective consecutive observational case series.

METHODS

Seventy-seven eyes from 75 consecutive patients who had undergone successful vitrectomies for idiopathic macular holes by a single surgeon with postoperative follow-ups for over 1 year were included. FAF imaging studies were performed 1 month and 6 months post surgery, and optical coherence tomography (OCT) was performed at regular intervals after surgery. The main outcome measures were macular hole size, FAF patterns, retina outer segment from OCT, and BCVA before and after operation.

RESULTS

The patients who had intact external limiting membranes (ELMs) at 1 month after surgery had better BCVAs than those without (P < .001), regardless of the photoreceptor inner segment/outer segment (IS/OS) condition. The FAF patterns were divided into 3 groups: homogenous hyperfluorescence, patchy hyperfluorescence, and normal hypofluorescence. No significant BCVA differences were noted (P = .28) among the 3 groups. However, significantly better BCVAs were noted in the patients who had both intact ELMs and normal hypofluorescence patterns (P = .011).

CONCLUSIONS

In sealed macular holes, intact ELMs predicted good postoperative BCVA. In this subgroup, a hypofluorescence pattern on the FAF imaging predicted the best postoperative BCVA.

Authors+Show Affiliations

Department of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23635418

Citation

Kao, Tzu-Yun, et al. "The Value of Combining Autofluorescence and Optical Coherence Tomography in Predicting the Visual Prognosis of Sealed Macular Holes." American Journal of Ophthalmology, vol. 156, no. 1, 2013, pp. 149-156.e1.
Kao TY, Yang CM, Yeh PT, et al. The value of combining autofluorescence and optical coherence tomography in predicting the visual prognosis of sealed macular holes. Am J Ophthalmol. 2013;156(1):149-156.e1.
Kao, T. Y., Yang, C. M., Yeh, P. T., Huang, J. Y., & Yang, C. H. (2013). The value of combining autofluorescence and optical coherence tomography in predicting the visual prognosis of sealed macular holes. American Journal of Ophthalmology, 156(1), 149-e1. https://doi.org/10.1016/j.ajo.2013.02.005
Kao TY, et al. The Value of Combining Autofluorescence and Optical Coherence Tomography in Predicting the Visual Prognosis of Sealed Macular Holes. Am J Ophthalmol. 2013;156(1):149-156.e1. PubMed PMID: 23635418.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The value of combining autofluorescence and optical coherence tomography in predicting the visual prognosis of sealed macular holes. AU - Kao,Tzu-Yun, AU - Yang,Chung-May, AU - Yeh,Po-Ting, AU - Huang,Jehn-Yu, AU - Yang,Chang-Hao, Y1 - 2013/04/28/ PY - 2012/10/31/received PY - 2013/02/05/revised PY - 2013/02/07/accepted PY - 2013/5/3/entrez PY - 2013/5/3/pubmed PY - 2013/9/7/medline SP - 149 EP - 156.e1 JF - American journal of ophthalmology JO - Am J Ophthalmol VL - 156 IS - 1 N2 - PURPOSE: To investigate the autofluorescence patterns of sealed macular holes and determine the correlations of the postoperative changes in spectral-domain optical coherence tomography and fundus autofluorescence (FAF) with the best-corrected visual acuity (BCVA) of patients with sealed idiopathic macular holes. DESIGN: Retrospective consecutive observational case series. METHODS: Seventy-seven eyes from 75 consecutive patients who had undergone successful vitrectomies for idiopathic macular holes by a single surgeon with postoperative follow-ups for over 1 year were included. FAF imaging studies were performed 1 month and 6 months post surgery, and optical coherence tomography (OCT) was performed at regular intervals after surgery. The main outcome measures were macular hole size, FAF patterns, retina outer segment from OCT, and BCVA before and after operation. RESULTS: The patients who had intact external limiting membranes (ELMs) at 1 month after surgery had better BCVAs than those without (P < .001), regardless of the photoreceptor inner segment/outer segment (IS/OS) condition. The FAF patterns were divided into 3 groups: homogenous hyperfluorescence, patchy hyperfluorescence, and normal hypofluorescence. No significant BCVA differences were noted (P = .28) among the 3 groups. However, significantly better BCVAs were noted in the patients who had both intact ELMs and normal hypofluorescence patterns (P = .011). CONCLUSIONS: In sealed macular holes, intact ELMs predicted good postoperative BCVA. In this subgroup, a hypofluorescence pattern on the FAF imaging predicted the best postoperative BCVA. SN - 1879-1891 UR - https://www.unboundmedicine.com/medline/citation/23635418/The_value_of_combining_autofluorescence_and_optical_coherence_tomography_in_predicting_the_visual_prognosis_of_sealed_macular_holes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9394(13)00112-8 DB - PRIME DP - Unbound Medicine ER -