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Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands.
J Org Chem. 2013 Jun 07; 78(11):5611-7.JO

Abstract

A highly efficient Cu-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using simple, stable, and easily prepared bis-sulfonamide diamine ligands was developed. The desired products were obtained in up to 99% yield with 96% ee.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Wu J
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China.
Wang D
No affiliation info available
Wu F
No affiliation info available
Wan B
No affiliation info available

MeSH

AlkylationCatalysisDiaminesIndolesLigandsMalonatesMesylatesMolecular StructureSulfonamides

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23642187

Citation

Wu, Jing, et al. "Cu(OTf)2-catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles With Arylidene Malonates Using Bis(sulfonamide)-diamine Ligands." The Journal of Organic Chemistry, vol. 78, no. 11, 2013, pp. 5611-7.
Wu J, Wang D, Wu F, et al. Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands. J Org Chem. 2013;78(11):5611-7.
Wu, J., Wang, D., Wu, F., & Wan, B. (2013). Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands. The Journal of Organic Chemistry, 78(11), 5611-7. https://doi.org/10.1021/jo400747d
Wu J, et al. Cu(OTf)2-catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles With Arylidene Malonates Using Bis(sulfonamide)-diamine Ligands. J Org Chem. 2013 Jun 7;78(11):5611-7. PubMed PMID: 23642187.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cu(OTf)2-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using bis(sulfonamide)-diamine ligands. AU - Wu,Jing, AU - Wang,Dongping, AU - Wu,Fan, AU - Wan,Boshun, Y1 - 2013/05/13/ PY - 2013/5/7/entrez PY - 2013/5/7/pubmed PY - 2013/12/20/medline SP - 5611 EP - 7 JF - The Journal of organic chemistry JO - J Org Chem VL - 78 IS - 11 N2 - A highly efficient Cu-catalyzed asymmetric Friedel-Crafts alkylation reaction of indoles with arylidene malonates using simple, stable, and easily prepared bis-sulfonamide diamine ligands was developed. The desired products were obtained in up to 99% yield with 96% ee. SN - 1520-6904 UR - https://www.unboundmedicine.com/medline/citation/23642187/Cu_OTf_2_catalyzed_asymmetric_Friedel_Crafts_alkylation_reaction_of_indoles_with_arylidene_malonates_using_bis_sulfonamide__diamine_ligands_ L2 - https://doi.org/10.1021/jo400747d DB - PRIME DP - Unbound Medicine ER -