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Probiotics and IBD.
Acta Gastroenterol Belg 2013; 76(1):15-9AG

Abstract

The pathophysiology of inflammatory bowel disease is still incompletely understood. While the development of the immune system and the establishment of the microflora take place during infancy young patients often have a more severe and extensive disease. The differences in composition and concentration of intestinal microbiota and aberrant immune responses towards the luminal bacteria prompted the concept of an 'ecological' approach to control the disease course. Probiotics, living, non pathogenic micro organisms with a beneficial effect on the host, and prebiotics, oligosaccharides promoting the growth of the beneficial microflora, have been studied to this effect. Results have so far been disappointing for Crohn's disease but encouraging for ulcerative colitis. An overview of studies using probiotics in adults or children and a perspective on specific pediatric issues is provided in this review.

Authors+Show Affiliations

Pediatric Gastroenterology, Hepatology and Nutrition, UZ Brussel, Belgium.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23650777

Citation

De Greef, Elisabeth, et al. "Probiotics and IBD." Acta Gastro-enterologica Belgica, vol. 76, no. 1, 2013, pp. 15-9.
De Greef E, Vandenplas Y, Hauser B, et al. Probiotics and IBD. Acta Gastroenterol Belg. 2013;76(1):15-9.
De Greef, E., Vandenplas, Y., Hauser, B., Devreker, T., & Veereman-Wauters, G. (2013). Probiotics and IBD. Acta Gastro-enterologica Belgica, 76(1), pp. 15-9.
De Greef E, et al. Probiotics and IBD. Acta Gastroenterol Belg. 2013;76(1):15-9. PubMed PMID: 23650777.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Probiotics and IBD. AU - De Greef,Elisabeth, AU - Vandenplas,Yvan, AU - Hauser,Bruno, AU - Devreker,Thierry, AU - Veereman-Wauters,Gigi, PY - 2013/5/9/entrez PY - 2013/5/9/pubmed PY - 2013/6/21/medline SP - 15 EP - 9 JF - Acta gastro-enterologica Belgica JO - Acta Gastroenterol. Belg. VL - 76 IS - 1 N2 - The pathophysiology of inflammatory bowel disease is still incompletely understood. While the development of the immune system and the establishment of the microflora take place during infancy young patients often have a more severe and extensive disease. The differences in composition and concentration of intestinal microbiota and aberrant immune responses towards the luminal bacteria prompted the concept of an 'ecological' approach to control the disease course. Probiotics, living, non pathogenic micro organisms with a beneficial effect on the host, and prebiotics, oligosaccharides promoting the growth of the beneficial microflora, have been studied to this effect. Results have so far been disappointing for Crohn's disease but encouraging for ulcerative colitis. An overview of studies using probiotics in adults or children and a perspective on specific pediatric issues is provided in this review. SN - 1784-3227 UR - https://www.unboundmedicine.com/medline/citation/23650777/Probiotics_and_IBD_ L2 - https://medlineplus.gov/crohnsdisease.html DB - PRIME DP - Unbound Medicine ER -