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Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study.
Br J Cancer 2013; 108(11):2381-9BJ

Abstract

BACKGROUND

Epidemiological evidence regarding the effect of coffee on the incidence of prostate cancer is inconsistent. We aimed to investigate coffee consumption and the risk of prostate cancer risk in a general Japanese population.

METHODS

We conducted a prospective cohort study in Ohsaki city, Japan, where 18 853 men aged 40-79 years participated in a baseline survey. Coffee consumption was assessed via a validated self-administered questionnaire. During 11 years of follow-up (from January 1 1995 to December 31, 2005), 318 incident cases of prostate cancer were detected. The Cox proportional hazards regression model was used to calculate the hazard ratios (HRs) and 95% confidence interval (CIs).

RESULTS

There was a significant inverse association between coffee consumption and the incidence risk of prostate cancer. Compared with those who did not drink coffee, the multivariate adjusted HRs were 0.81 (95% CI: 0.61-1.07), 0.73 (95% CI: 0.53-1.00), and 0.63 (095% CI: 0.39-1.00) for those who drank coffee occasionally, 1-2 cups per day, and > or =3 cups per day, respectively, with a P for trend of 0.02.

CONCLUSION

This prospective finding from a Japanese population adds evidence that coffee intake is inversely associated with the incidence of prostate cancer.

Authors+Show Affiliations

Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan. liqiangda@yahoo.com.cn

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23674088

Citation

Li, Q, et al. "Coffee Consumption and the Risk of Prostate Cancer: the Ohsaki Cohort Study." British Journal of Cancer, vol. 108, no. 11, 2013, pp. 2381-9.
Li Q, Kakizaki M, Sugawara Y, et al. Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study. Br J Cancer. 2013;108(11):2381-9.
Li, Q., Kakizaki, M., Sugawara, Y., Tomata, Y., Watanabe, T., Nishino, Y., & Tsuji, I. (2013). Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study. British Journal of Cancer, 108(11), pp. 2381-9. doi:10.1038/bjc.2013.238.
Li Q, et al. Coffee Consumption and the Risk of Prostate Cancer: the Ohsaki Cohort Study. Br J Cancer. 2013 Jun 11;108(11):2381-9. PubMed PMID: 23674088.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Coffee consumption and the risk of prostate cancer: the Ohsaki Cohort Study. AU - Li,Q, AU - Kakizaki,M, AU - Sugawara,Y, AU - Tomata,Y, AU - Watanabe,T, AU - Nishino,Y, AU - Tsuji,I, Y1 - 2013/05/14/ PY - 2013/5/16/entrez PY - 2013/5/16/pubmed PY - 2013/9/18/medline SP - 2381 EP - 9 JF - British journal of cancer JO - Br. J. Cancer VL - 108 IS - 11 N2 - BACKGROUND: Epidemiological evidence regarding the effect of coffee on the incidence of prostate cancer is inconsistent. We aimed to investigate coffee consumption and the risk of prostate cancer risk in a general Japanese population. METHODS: We conducted a prospective cohort study in Ohsaki city, Japan, where 18 853 men aged 40-79 years participated in a baseline survey. Coffee consumption was assessed via a validated self-administered questionnaire. During 11 years of follow-up (from January 1 1995 to December 31, 2005), 318 incident cases of prostate cancer were detected. The Cox proportional hazards regression model was used to calculate the hazard ratios (HRs) and 95% confidence interval (CIs). RESULTS: There was a significant inverse association between coffee consumption and the incidence risk of prostate cancer. Compared with those who did not drink coffee, the multivariate adjusted HRs were 0.81 (95% CI: 0.61-1.07), 0.73 (95% CI: 0.53-1.00), and 0.63 (095% CI: 0.39-1.00) for those who drank coffee occasionally, 1-2 cups per day, and > or =3 cups per day, respectively, with a P for trend of 0.02. CONCLUSION: This prospective finding from a Japanese population adds evidence that coffee intake is inversely associated with the incidence of prostate cancer. SN - 1532-1827 UR - https://www.unboundmedicine.com/medline/citation/23674088/Coffee_consumption_and_the_risk_of_prostate_cancer:_the_Ohsaki_Cohort_Study_ L2 - http://dx.doi.org/10.1038/bjc.2013.238 DB - PRIME DP - Unbound Medicine ER -