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Magnesium in disease prevention and overall health.
Adv Nutr. 2013 May 01; 4(3):378S-83S.AN

Abstract

Magnesium is the fourth most abundant mineral and the second most abundant intracellular divalent cation and has been recognized as a cofactor for >300 metabolic reactions in the body. Some of the processes in which magnesium is a cofactor include, but are not limited to, protein synthesis, cellular energy production and storage, reproduction, DNA and RNA synthesis, and stabilizing mitochondrial membranes. Magnesium also plays a critical role in nerve transmission, cardiac excitability, neuromuscular conduction, muscular contraction, vasomotor tone, blood pressure, and glucose and insulin metabolism. Because of magnesium's many functions within the body, it plays a major role in disease prevention and overall health. Low levels of magnesium have been associated with a number of chronic diseases including migraine headaches, Alzheimer's disease, cerebrovascular accident (stroke), hypertension, cardiovascular disease, and type 2 diabetes mellitus. Good food sources of magnesium include unrefined (whole) grains, spinach, nuts, legumes, and white potatoes (tubers). This review presents recent research in the areas of magnesium and chronic disease, with the goal of emphasizing magnesium's role in disease prevention and overall health.

Authors+Show Affiliations

Department of Nutrition Sciences, Center for Integrated Nutrition & Performance College of Nursing and Health Professions Drexel University, Philadelphia, PA, USA. Stella.L.Volpe@drexel.edu

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

23674807

Citation

Volpe, Stella Lucia. "Magnesium in Disease Prevention and Overall Health." Advances in Nutrition (Bethesda, Md.), vol. 4, no. 3, 2013, 378S-83S.
Volpe SL. Magnesium in disease prevention and overall health. Adv Nutr. 2013;4(3):378S-83S.
Volpe, S. L. (2013). Magnesium in disease prevention and overall health. Advances in Nutrition (Bethesda, Md.), 4(3), 378S-83S. https://doi.org/10.3945/an.112.003483
Volpe SL. Magnesium in Disease Prevention and Overall Health. Adv Nutr. 2013 May 1;4(3):378S-83S. PubMed PMID: 23674807.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Magnesium in disease prevention and overall health. A1 - Volpe,Stella Lucia, Y1 - 2013/05/01/ PY - 2013/5/16/entrez PY - 2013/5/16/pubmed PY - 2013/12/16/medline SP - 378S EP - 83S JF - Advances in nutrition (Bethesda, Md.) JO - Adv Nutr VL - 4 IS - 3 N2 - Magnesium is the fourth most abundant mineral and the second most abundant intracellular divalent cation and has been recognized as a cofactor for >300 metabolic reactions in the body. Some of the processes in which magnesium is a cofactor include, but are not limited to, protein synthesis, cellular energy production and storage, reproduction, DNA and RNA synthesis, and stabilizing mitochondrial membranes. Magnesium also plays a critical role in nerve transmission, cardiac excitability, neuromuscular conduction, muscular contraction, vasomotor tone, blood pressure, and glucose and insulin metabolism. Because of magnesium's many functions within the body, it plays a major role in disease prevention and overall health. Low levels of magnesium have been associated with a number of chronic diseases including migraine headaches, Alzheimer's disease, cerebrovascular accident (stroke), hypertension, cardiovascular disease, and type 2 diabetes mellitus. Good food sources of magnesium include unrefined (whole) grains, spinach, nuts, legumes, and white potatoes (tubers). This review presents recent research in the areas of magnesium and chronic disease, with the goal of emphasizing magnesium's role in disease prevention and overall health. SN - 2156-5376 UR - https://www.unboundmedicine.com/medline/citation/23674807/Magnesium_in_disease_prevention_and_overall_health_ L2 - https://academic.oup.com/advances/article-lookup/doi/10.3945/an.112.003483 DB - PRIME DP - Unbound Medicine ER -