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Low-dose manic switch and high-dose antimanic effect and extrapyramidal symptoms by aripiprazole in a single bipolar patient.
Am J Ther. 2014 Nov-Dec; 21(6):e218-20.AJ

Abstract

A case report of an adult female patient with bipolar depression who developed mania after short-term administration of low-dose aripiprazole (2 mg daily) is reported. Later, the author rechallenged with high-dose aripiprazole (22 mg) for treating mania, but there was no manic switch, unlike when using low-dose aripiprazole. A 1-month follow-up revealed no further symptoms of mania or depression, except dyskinesia and sialorrhea. Clinicians should therefore carefully and vigilantly monitor for both the induction of mania and extrapyramidal symptoms according to the aripiprazole dose.

Authors+Show Affiliations

Department of Psychiatry, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Korea.

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23676345

Citation

Park, Young-Min. "Low-dose Manic Switch and High-dose Antimanic Effect and Extrapyramidal Symptoms By Aripiprazole in a Single Bipolar Patient." American Journal of Therapeutics, vol. 21, no. 6, 2014, pp. e218-20.
Park YM. Low-dose manic switch and high-dose antimanic effect and extrapyramidal symptoms by aripiprazole in a single bipolar patient. Am J Ther. 2014;21(6):e218-20.
Park, Y. M. (2014). Low-dose manic switch and high-dose antimanic effect and extrapyramidal symptoms by aripiprazole in a single bipolar patient. American Journal of Therapeutics, 21(6), e218-20. https://doi.org/10.1097/MJT.0b013e31828e5d0b
Park YM. Low-dose Manic Switch and High-dose Antimanic Effect and Extrapyramidal Symptoms By Aripiprazole in a Single Bipolar Patient. Am J Ther. 2014 Nov-Dec;21(6):e218-20. PubMed PMID: 23676345.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Low-dose manic switch and high-dose antimanic effect and extrapyramidal symptoms by aripiprazole in a single bipolar patient. A1 - Park,Young-Min, PY - 2013/5/17/entrez PY - 2013/5/17/pubmed PY - 2015/7/7/medline SP - e218 EP - 20 JF - American journal of therapeutics JO - Am J Ther VL - 21 IS - 6 N2 - A case report of an adult female patient with bipolar depression who developed mania after short-term administration of low-dose aripiprazole (2 mg daily) is reported. Later, the author rechallenged with high-dose aripiprazole (22 mg) for treating mania, but there was no manic switch, unlike when using low-dose aripiprazole. A 1-month follow-up revealed no further symptoms of mania or depression, except dyskinesia and sialorrhea. Clinicians should therefore carefully and vigilantly monitor for both the induction of mania and extrapyramidal symptoms according to the aripiprazole dose. SN - 1536-3686 UR - https://www.unboundmedicine.com/medline/citation/23676345/Low_dose_manic_switch_and_high_dose_antimanic_effect_and_extrapyramidal_symptoms_by_aripiprazole_in_a_single_bipolar_patient_ L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=23676345.ui DB - PRIME DP - Unbound Medicine ER -