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[Visceral leishmaniasis in patient with HIV infection].
Rev Chilena Infectol. 2013 Apr; 30(2):216-20.RC

Abstract

Leishmaniasis is a parasitic disease caused by the protozoa of the genus Leishmania transmitted by sandfly bites. It causes subclinical infection and diverse clinical manifestations with cutaneous, mucosal or visceral involvement. The last one, called visceral leishmaniasis, is usually fatal without treatment and in VIH patients with deep immunosuppression, has been recognized as an opportunistic infection with a high degree of difficulty in diagnosis and treatment. We present the case of a patient with HIV infection and visceral leishmaniasis. The clinical presentation was a prolonged febril syndrome with hepatosplenomegaly, lymphadenopathy and pancytopenia. The differential diagnosis was made with lymphoma and other opportunistic infections, as mycobacteriosis. The bone marrow aspirate reveled parasite amastigotes. The patient received treatment with amphotericin B deoxycholate for 14 days and 2 months after he relapsed. Then he was treated with the same drug for 21 days and after that he has been in prophylaxis for 29 months with good outcome, without any other relapse.

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Authors+Show Affiliations

Olea P
Hospital de Enfermedades Infecciosas Dr. Lucio Córdova, Chile. pilaroleam@gmail.com
Pinilla J
No affiliation info available

MeSH

AIDS-Related Opportunistic InfectionsAmphotericin BAntiprotozoal AgentsHumansLeishmaniasis, VisceralMaleMiddle Aged

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

23677161

Citation

Olea, Pilar, and Jorge Pinilla. "[Visceral Leishmaniasis in Patient With HIV Infection]." Revista Chilena De Infectologia : Organo Oficial De La Sociedad Chilena De Infectologia, vol. 30, no. 2, 2013, pp. 216-20.
Olea P, Pinilla J. [Visceral leishmaniasis in patient with HIV infection]. Rev Chilena Infectol. 2013;30(2):216-20.
Olea, P., & Pinilla, J. (2013). [Visceral leishmaniasis in patient with HIV infection]. Revista Chilena De Infectologia : Organo Oficial De La Sociedad Chilena De Infectologia, 30(2), 216-20. https://doi.org/10.4067/S0716-10182013000200013
Olea P, Pinilla J. [Visceral Leishmaniasis in Patient With HIV Infection]. Rev Chilena Infectol. 2013;30(2):216-20. PubMed PMID: 23677161.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Visceral leishmaniasis in patient with HIV infection]. AU - Olea,Pilar, AU - Pinilla,Jorge, PY - 2012/04/06/received PY - 2012/12/14/accepted PY - 2013/5/17/entrez PY - 2013/5/17/pubmed PY - 2013/10/18/medline SP - 216 EP - 20 JF - Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia JO - Rev Chilena Infectol VL - 30 IS - 2 N2 - Leishmaniasis is a parasitic disease caused by the protozoa of the genus Leishmania transmitted by sandfly bites. It causes subclinical infection and diverse clinical manifestations with cutaneous, mucosal or visceral involvement. The last one, called visceral leishmaniasis, is usually fatal without treatment and in VIH patients with deep immunosuppression, has been recognized as an opportunistic infection with a high degree of difficulty in diagnosis and treatment. We present the case of a patient with HIV infection and visceral leishmaniasis. The clinical presentation was a prolonged febril syndrome with hepatosplenomegaly, lymphadenopathy and pancytopenia. The differential diagnosis was made with lymphoma and other opportunistic infections, as mycobacteriosis. The bone marrow aspirate reveled parasite amastigotes. The patient received treatment with amphotericin B deoxycholate for 14 days and 2 months after he relapsed. Then he was treated with the same drug for 21 days and after that he has been in prophylaxis for 29 months with good outcome, without any other relapse. SN - 0716-1018 UR - https://www.unboundmedicine.com/medline/citation/23677161/[Visceral_leishmaniasis_in_patient_with_HIV_infection]_ L2 - http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182013000200013&lng=en&nrm=iso&tlng=en DB - PRIME DP - Unbound Medicine ER -