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Surgery and proton pump inhibitors for treatment of vocal process granulomas.
Eur Arch Otorhinolaryngol. 2013 Nov; 270(11):2921-6.EA

Abstract

The aim of this study was to analyze the outcomes of vocal process granulomas treated with surgery and proton pump inhibitors and to specify related factors of recurrence. The medical records of patients with diagnosis of vocal process granuloma between 2000 and 2012 were reviewed. All patients were treated with surgery and proton pump inhibitors for at least 1 month. Forty-one patients were reviewed; mean follow-up time was 45 months. There was no recurrence among the patients who had a recent history of intubation. The recurrence rates of contact granuloma was 38.7 %, and significantly related to the frequency of surgery (P = 0.042), but was not significantly associated with the history of acid reflux (P = 0.676) and vocal abuse (P = 0.447), lesion size (P = 0.203) or surgical techniques (P = 0.331). Surgery combined with proton pump inhibitors was partially effective for the vocal process granulomas, especially with intubated patients. However, repeat surgery for recurrent contact granuloma should be preceded with caution due to high recurrence rates.

Authors+Show Affiliations

Department of Otolaryngology, Affiliated Eye and Ear, Nose and Throat Hospital, Shanghai Medical College, Fudan University, Fen-yang Road 83, Shanghai, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Observational Study

Language

eng

PubMed ID

23677453

Citation

Hong-Gang, Duan, et al. "Surgery and Proton Pump Inhibitors for Treatment of Vocal Process Granulomas." European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated With the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, vol. 270, no. 11, 2013, pp. 2921-6.
Hong-Gang D, He-Juan J, Chun-Quan Z, et al. Surgery and proton pump inhibitors for treatment of vocal process granulomas. Eur Arch Otorhinolaryngol. 2013;270(11):2921-6.
Hong-Gang, D., He-Juan, J., Chun-Quan, Z., & Guo-Kang, F. (2013). Surgery and proton pump inhibitors for treatment of vocal process granulomas. European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated With the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(11), 2921-6. https://doi.org/10.1007/s00405-013-2527-8
Hong-Gang D, et al. Surgery and Proton Pump Inhibitors for Treatment of Vocal Process Granulomas. Eur Arch Otorhinolaryngol. 2013;270(11):2921-6. PubMed PMID: 23677453.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Surgery and proton pump inhibitors for treatment of vocal process granulomas. AU - Hong-Gang,Duan, AU - He-Juan,Jin, AU - Chun-Quan,Zheng, AU - Guo-Kang,Fan, Y1 - 2013/05/16/ PY - 2012/12/20/received PY - 2013/04/22/accepted PY - 2013/5/17/entrez PY - 2013/5/17/pubmed PY - 2014/5/27/medline SP - 2921 EP - 6 JF - European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery JO - Eur Arch Otorhinolaryngol VL - 270 IS - 11 N2 - The aim of this study was to analyze the outcomes of vocal process granulomas treated with surgery and proton pump inhibitors and to specify related factors of recurrence. The medical records of patients with diagnosis of vocal process granuloma between 2000 and 2012 were reviewed. All patients were treated with surgery and proton pump inhibitors for at least 1 month. Forty-one patients were reviewed; mean follow-up time was 45 months. There was no recurrence among the patients who had a recent history of intubation. The recurrence rates of contact granuloma was 38.7 %, and significantly related to the frequency of surgery (P = 0.042), but was not significantly associated with the history of acid reflux (P = 0.676) and vocal abuse (P = 0.447), lesion size (P = 0.203) or surgical techniques (P = 0.331). Surgery combined with proton pump inhibitors was partially effective for the vocal process granulomas, especially with intubated patients. However, repeat surgery for recurrent contact granuloma should be preceded with caution due to high recurrence rates. SN - 1434-4726 UR - https://www.unboundmedicine.com/medline/citation/23677453/Surgery_and_proton_pump_inhibitors_for_treatment_of_vocal_process_granulomas_ L2 - https://dx.doi.org/10.1007/s00405-013-2527-8 DB - PRIME DP - Unbound Medicine ER -