[Metabolic control and acceptance of a regimen of multiple injections using an insulin (novopen) injector in a group of juvenile diabetics].An Esp Pediatr. 1990 Apr; 32(4):299-302.AE
A multiple insulin injection (MII) regimen using a pen injector (novopén) was compared with conventional therapy in order to cases metabolic control and acceptability. Ten young diabetic patients completed the 12-month study period. Mean glycosylated haemoglobin (HbA1) fell over the study period from 12.30 +/- 2.53% (mean +/- SD) at the end of conventional therapy to 11.10 +/- 1.29% after 6 months of MII regimen (NS) and 10.20 +/- 1.37% at the end of the study period, significant difference (p less than 0.05). Plasma cholesterol remained unchanged. A self-completed questionnaire was performed after 6 months of MII regimen using novopén. The pen injector was very well accepted and all diabetics preferred to continue with this therapeutic regimen.