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The role of β-adrenergic blockers in Parkinson's disease: possible genetic and cell-signaling mechanisms.
Am J Alzheimers Dis Other Demen 2013; 28(4):306-17AJ

Abstract

Genetic studies have identified numerous factors linking β-adrenergic blockade to Parkinson's disease (PD), including human leukocyte antigen genes, the renin-angiotensin system, poly(adenosine diphosphate-ribose) polymerase 1, nerve growth factor, vascular endothelial growth factor, and the reduced form of nicotinamide adenine dinucleotide phosphate. β-Adrenergic blockade has also been implicated in PD via its effects on matrix metalloproteinases, mitogen-activated protein kinase pathways, prostaglandins, cyclooxygenase 2, and nitric oxide synthase. β-Adrenergic blockade may have a significant role in PD; therefore, the characterization of β-adrenergic blockade in patients with PD is needed.

Authors+Show Affiliations

Vietnamese American Medical Research Foundation, Westminster, CA 92683, USA. lng2687765@aol.comNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23695225

Citation

Luong, Khanh vinh quoc, and Lan Thi Hoàng Nguyen. "The Role of Β-adrenergic Blockers in Parkinson's Disease: Possible Genetic and Cell-signaling Mechanisms." American Journal of Alzheimer's Disease and Other Dementias, vol. 28, no. 4, 2013, pp. 306-17.
Luong Kv, Nguyen LT. The role of β-adrenergic blockers in Parkinson's disease: possible genetic and cell-signaling mechanisms. Am J Alzheimers Dis Other Demen. 2013;28(4):306-17.
Luong, K. v., & Nguyen, L. T. (2013). The role of β-adrenergic blockers in Parkinson's disease: possible genetic and cell-signaling mechanisms. American Journal of Alzheimer's Disease and Other Dementias, 28(4), pp. 306-17. doi:10.1177/1533317513488919.
Luong Kv, Nguyen LT. The Role of Β-adrenergic Blockers in Parkinson's Disease: Possible Genetic and Cell-signaling Mechanisms. Am J Alzheimers Dis Other Demen. 2013;28(4):306-17. PubMed PMID: 23695225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The role of β-adrenergic blockers in Parkinson's disease: possible genetic and cell-signaling mechanisms. AU - Luong,Khanh vinh quoc, AU - Nguyen,Lan Thi Hoàng, Y1 - 2013/05/21/ PY - 2013/5/23/entrez PY - 2013/5/23/pubmed PY - 2013/10/23/medline KW - Parkinson’s disease KW - tremor KW - β-adrenergic antagonism KW - β-adrenergic blocker SP - 306 EP - 17 JF - American journal of Alzheimer's disease and other dementias JO - Am J Alzheimers Dis Other Demen VL - 28 IS - 4 N2 - Genetic studies have identified numerous factors linking β-adrenergic blockade to Parkinson's disease (PD), including human leukocyte antigen genes, the renin-angiotensin system, poly(adenosine diphosphate-ribose) polymerase 1, nerve growth factor, vascular endothelial growth factor, and the reduced form of nicotinamide adenine dinucleotide phosphate. β-Adrenergic blockade has also been implicated in PD via its effects on matrix metalloproteinases, mitogen-activated protein kinase pathways, prostaglandins, cyclooxygenase 2, and nitric oxide synthase. β-Adrenergic blockade may have a significant role in PD; therefore, the characterization of β-adrenergic blockade in patients with PD is needed. SN - 1938-2731 UR - https://www.unboundmedicine.com/medline/citation/23695225/The_role_of_β_adrenergic_blockers_in_Parkinson's_disease:_possible_genetic_and_cell_signaling_mechanisms_ L2 - http://journals.sagepub.com/doi/full/10.1177/1533317513488919?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -