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Solitary epidermolytic acanthoma.
J Cutan Pathol. 2013 Aug; 40(8):701-7.JC

Abstract

BACKGROUND

Solitary epidermolytic acanthoma is thought to be an uncommon lesion. It can present as a solitary, localized or disseminated process that is unrelated to the genetic form of icthyosis.

METHODS

A retrospective review of solitary epidermolytic acanthomas was performed at the Ackerman Academy of Dermatopathology, NY, over a 2 year period. The clinical and histopathological features of solitary epidermolytic acanthomas were described in 64 biopsies from 60 individuals. In situ hybridization for human papillomavirus (HPV) was performed on all genital lesions.

RESULTS

The incidence of epidermolytic acanthomas in our series was higher than previously reported (27.8/100,000). Genital location was the most common and the incidence of genital lesions was 8/100,000. In situ hybridization showed no evidence of genital HPV types within the lesions. The histological features of solitary epidermolytic acanthoma were re-evaluated.

CONCLUSIONS

Genital skin was the most common location for solitary epidermolytic acanthoma, but we found no evidence to suggest a role for genital HPV types. A strong male predominance was noted, and the lesions demonstrate a wide range of clinical and pathological findings.

Authors+Show Affiliations

Ackerman Academy of Dermatopathology, New York, NY 10016, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23710687

Citation

Kazlouskaya, Viktoryia, et al. "Solitary Epidermolytic Acanthoma." Journal of Cutaneous Pathology, vol. 40, no. 8, 2013, pp. 701-7.
Kazlouskaya V, Lambe J, Elston D. Solitary epidermolytic acanthoma. J Cutan Pathol. 2013;40(8):701-7.
Kazlouskaya, V., Lambe, J., & Elston, D. (2013). Solitary epidermolytic acanthoma. Journal of Cutaneous Pathology, 40(8), 701-7. https://doi.org/10.1111/cup.12165
Kazlouskaya V, Lambe J, Elston D. Solitary Epidermolytic Acanthoma. J Cutan Pathol. 2013;40(8):701-7. PubMed PMID: 23710687.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Solitary epidermolytic acanthoma. AU - Kazlouskaya,Viktoryia, AU - Lambe,Jennifer, AU - Elston,Dirk, Y1 - 2013/05/24/ PY - 2012/03/30/received PY - 2012/05/08/revised PY - 2012/06/17/accepted PY - 2013/5/29/entrez PY - 2013/5/29/pubmed PY - 2014/2/5/medline KW - epidermolytic acanthoma KW - epidermolytic hyperkeratosis KW - genitalia KW - perinuclear bands SP - 701 EP - 7 JF - Journal of cutaneous pathology JO - J. Cutan. Pathol. VL - 40 IS - 8 N2 - BACKGROUND: Solitary epidermolytic acanthoma is thought to be an uncommon lesion. It can present as a solitary, localized or disseminated process that is unrelated to the genetic form of icthyosis. METHODS: A retrospective review of solitary epidermolytic acanthomas was performed at the Ackerman Academy of Dermatopathology, NY, over a 2 year period. The clinical and histopathological features of solitary epidermolytic acanthomas were described in 64 biopsies from 60 individuals. In situ hybridization for human papillomavirus (HPV) was performed on all genital lesions. RESULTS: The incidence of epidermolytic acanthomas in our series was higher than previously reported (27.8/100,000). Genital location was the most common and the incidence of genital lesions was 8/100,000. In situ hybridization showed no evidence of genital HPV types within the lesions. The histological features of solitary epidermolytic acanthoma were re-evaluated. CONCLUSIONS: Genital skin was the most common location for solitary epidermolytic acanthoma, but we found no evidence to suggest a role for genital HPV types. A strong male predominance was noted, and the lesions demonstrate a wide range of clinical and pathological findings. SN - 1600-0560 UR - https://www.unboundmedicine.com/medline/citation/23710687/Solitary_epidermolytic_acanthoma_ L2 - https://doi.org/10.1111/cup.12165 DB - PRIME DP - Unbound Medicine ER -