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[An epidemiological survey of the prevalence of thyroid diseases in mild iodine deficiency city after salt iodization].
Zhonghua Nei Ke Za Zhi. 2013 Jan; 52(1):16-20.ZN

Abstract

OBJECTIVE

To investigate the current status of iodine nutrition and the prevalence of thyroid diseases in Guiyang, a mild iodine deficiency city practiced salt iodization for 25 years.

METHODS

A representative sample of 1509 adults aged 20 years old or above in Guiyang, selected by a multistage stratified sampling method, participated in the study. After an overnight fasting, serum thyroid hormones, serum thyroid autoantibodies, and urine iodine were measured. B-mode ultrasonography of the thyroid was performed in the population. Meanwhile, urine iodine of 80 children aged 8 - 10 years old in the same community were measured after an overnight fasting.

RESULTS

The median of 8-10 years old children's urinary iodine was 228.7 µg/L. The prevalence of overt hypothyroidism, subclinical hypothyroidism, overt hyperthyroidism and subclinical hyperthyroidism was 1.79%, 14.12%, 1.52% and 1.06% respectively. The prevalence of subclinical hypothyroidism was significantly higher than overt hypothyroidism (P < 0.05) and was significantly higher in female than that in male (P < 0.05). The prevalence of positive thyroid peroxidase antibody, positive thyroglobulin antibody and autoimmune thyroiditis was 14.38%, 13.59% and 4.44% respectively, which were significantly higher in female than that in male (all P values < 0.05). The prevalence of diffuse goiter and nodular goiter was 0.86% and 0.20% respectively, with a significant difference (P < 0.05).

CONCLUSION

After 25 years of salt iodization, the iodine nutrition in Guiyang is more than adequate with high prevalence of overt hypothyroidism, subclinical hypothyroidism and autoimmune thyroiditis.

Authors+Show Affiliations

Department of Endocrinology, Affiliated Hospital of Guiyang Medical College, Guiyang, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

23710809

Citation

Peng, Nian-chun, et al. "[An Epidemiological Survey of the Prevalence of Thyroid Diseases in Mild Iodine Deficiency City After Salt Iodization]." Zhonghua Nei Ke Za Zhi, vol. 52, no. 1, 2013, pp. 16-20.
Peng NC, Shi LX, Zhang Q, et al. [An epidemiological survey of the prevalence of thyroid diseases in mild iodine deficiency city after salt iodization]. Zhonghua Nei Ke Za Zhi. 2013;52(1):16-20.
Peng, N. C., Shi, L. X., Zhang, Q., Xu, S. J., Li, H., Zhang, M., Zhang, S., Zhuang, H. J., Gong, M. X., Wang, R., Wu, D. R., Hu, Y., & Liu, L. (2013). [An epidemiological survey of the prevalence of thyroid diseases in mild iodine deficiency city after salt iodization]. Zhonghua Nei Ke Za Zhi, 52(1), 16-20.
Peng NC, et al. [An Epidemiological Survey of the Prevalence of Thyroid Diseases in Mild Iodine Deficiency City After Salt Iodization]. Zhonghua Nei Ke Za Zhi. 2013;52(1):16-20. PubMed PMID: 23710809.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [An epidemiological survey of the prevalence of thyroid diseases in mild iodine deficiency city after salt iodization]. AU - Peng,Nian-chun, AU - Shi,Li-xin, AU - Zhang,Qiao, AU - Xu,Shu-jing, AU - Li,Hong, AU - Zhang,Miao, AU - Zhang,Song, AU - Zhuang,Hui-jun, AU - Gong,Ming-xian, AU - Wang,Rui, AU - Wu,Dan-rong, AU - Hu,Ying, AU - Liu,Lu, PY - 2013/5/29/entrez PY - 2013/5/29/pubmed PY - 2014/5/16/medline SP - 16 EP - 20 JF - Zhonghua nei ke za zhi JO - Zhonghua Nei Ke Za Zhi VL - 52 IS - 1 N2 - OBJECTIVE: To investigate the current status of iodine nutrition and the prevalence of thyroid diseases in Guiyang, a mild iodine deficiency city practiced salt iodization for 25 years. METHODS: A representative sample of 1509 adults aged 20 years old or above in Guiyang, selected by a multistage stratified sampling method, participated in the study. After an overnight fasting, serum thyroid hormones, serum thyroid autoantibodies, and urine iodine were measured. B-mode ultrasonography of the thyroid was performed in the population. Meanwhile, urine iodine of 80 children aged 8 - 10 years old in the same community were measured after an overnight fasting. RESULTS: The median of 8-10 years old children's urinary iodine was 228.7 µg/L. The prevalence of overt hypothyroidism, subclinical hypothyroidism, overt hyperthyroidism and subclinical hyperthyroidism was 1.79%, 14.12%, 1.52% and 1.06% respectively. The prevalence of subclinical hypothyroidism was significantly higher than overt hypothyroidism (P < 0.05) and was significantly higher in female than that in male (P < 0.05). The prevalence of positive thyroid peroxidase antibody, positive thyroglobulin antibody and autoimmune thyroiditis was 14.38%, 13.59% and 4.44% respectively, which were significantly higher in female than that in male (all P values < 0.05). The prevalence of diffuse goiter and nodular goiter was 0.86% and 0.20% respectively, with a significant difference (P < 0.05). CONCLUSION: After 25 years of salt iodization, the iodine nutrition in Guiyang is more than adequate with high prevalence of overt hypothyroidism, subclinical hypothyroidism and autoimmune thyroiditis. SN - 0578-1426 UR - https://www.unboundmedicine.com/medline/citation/23710809/[An_epidemiological_survey_of_the_prevalence_of_thyroid_diseases_in_mild_iodine_deficiency_city_after_salt_iodization]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0578-1426&amp;year=2013&amp;vol=52&amp;issue=1&amp;fpage=16 DB - PRIME DP - Unbound Medicine ER -