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Association of fish consumption and Ω 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis.
Int J Neurosci 2013; 123(11):792-800IJ

Abstract

The role of fish consumption and omega 3 supplementation in multiple sclerosis (MS) is controversial, although there is some evidence to support a beneficial effect. We surveyed a large cohort of people with MS recruited via Web 2.0 platforms, requesting information on type of MS, relapse rates, disability, health-related quality of life, frequency of fish consumption and omega 3 supplementation, including type and dose, using validated tools where possible. We aimed to determine whether there was an association between fish consumption and omega 3 supplementation and quality of life, disability and disease activity for people with MS. Univariate and multivariate analyses were undertaken. Of 2469 respondents, 1493 (60.5%) had relapsing-remitting MS. Those consuming fish more frequently and those taking omega 3 supplements had significantly better quality of life, in all domains, and less disability. For fish consumption, there was a clear dose-response relationship for these associations. There were also trends towards lower relapse rates and reduced disease activity; flaxseed oil supplementation was associated with over 60% lower relapse rate over the previous 12 months. Further dietary studies and randomised controlled trials of omega 3 supplementation for people with MS are required, preferably using flaxseed oil.

Authors+Show Affiliations

1Emergency Practice Innovation Centre, St Vincents Hospital , Fitzroy , Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23713615

Citation

Jelinek, George A., et al. "Association of Fish Consumption and Ω 3 Supplementation With Quality of Life, Disability and Disease Activity in an International Cohort of People With Multiple Sclerosis." The International Journal of Neuroscience, vol. 123, no. 11, 2013, pp. 792-800.
Jelinek GA, Hadgkiss EJ, Weiland TJ, et al. Association of fish consumption and Ω 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis. Int J Neurosci. 2013;123(11):792-800.
Jelinek, G. A., Hadgkiss, E. J., Weiland, T. J., Pereira, N. G., Marck, C. H., & van der Meer, D. M. (2013). Association of fish consumption and Ω 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis. The International Journal of Neuroscience, 123(11), pp. 792-800. doi:10.3109/00207454.2013.803104.
Jelinek GA, et al. Association of Fish Consumption and Ω 3 Supplementation With Quality of Life, Disability and Disease Activity in an International Cohort of People With Multiple Sclerosis. Int J Neurosci. 2013;123(11):792-800. PubMed PMID: 23713615.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Association of fish consumption and Ω 3 supplementation with quality of life, disability and disease activity in an international cohort of people with multiple sclerosis. AU - Jelinek,George A, AU - Hadgkiss,Emily J, AU - Weiland,Tracey J, AU - Pereira,Naresh G, AU - Marck,Claudia H, AU - van der Meer,Dania M, Y1 - 2013/06/03/ PY - 2013/5/30/entrez PY - 2013/5/30/pubmed PY - 2014/5/20/medline SP - 792 EP - 800 JF - The International journal of neuroscience JO - Int. J. Neurosci. VL - 123 IS - 11 N2 - The role of fish consumption and omega 3 supplementation in multiple sclerosis (MS) is controversial, although there is some evidence to support a beneficial effect. We surveyed a large cohort of people with MS recruited via Web 2.0 platforms, requesting information on type of MS, relapse rates, disability, health-related quality of life, frequency of fish consumption and omega 3 supplementation, including type and dose, using validated tools where possible. We aimed to determine whether there was an association between fish consumption and omega 3 supplementation and quality of life, disability and disease activity for people with MS. Univariate and multivariate analyses were undertaken. Of 2469 respondents, 1493 (60.5%) had relapsing-remitting MS. Those consuming fish more frequently and those taking omega 3 supplements had significantly better quality of life, in all domains, and less disability. For fish consumption, there was a clear dose-response relationship for these associations. There were also trends towards lower relapse rates and reduced disease activity; flaxseed oil supplementation was associated with over 60% lower relapse rate over the previous 12 months. Further dietary studies and randomised controlled trials of omega 3 supplementation for people with MS are required, preferably using flaxseed oil. SN - 1563-5279 UR - https://www.unboundmedicine.com/medline/citation/23713615/Association_of_fish_consumption_and_Ω_3_supplementation_with_quality_of_life_disability_and_disease_activity_in_an_international_cohort_of_people_with_multiple_sclerosis_ L2 - http://www.tandfonline.com/doi/full/10.3109/00207454.2013.803104 DB - PRIME DP - Unbound Medicine ER -