TY - JOUR T1 - Effects of open-irrigated radiofrequency ablation catheter design on lesion formation and complications: in vitro comparison of 6 different devices. AU - Guerra,Jose M, AU - Jorge,Esther, AU - Raga,Silvia, AU - Gálvez-Montón,Carolina, AU - Alonso-Martín,Concepción, AU - Rodríguez-Font,Enrique, AU - Cinca,Juan, AU - Viñolas,Xavier, Y1 - 2013/05/29/ PY - 2013/01/19/received PY - 2013/04/07/revised PY - 2013/04/16/accepted PY - 2013/5/31/entrez PY - 2013/5/31/pubmed PY - 2015/7/21/medline KW - atrial fibrillation KW - catheter ablation KW - irrigated catheter KW - lesion size KW - radiofrequency ablation SP - 1157 EP - 62 JF - Journal of cardiovascular electrophysiology JO - J Cardiovasc Electrophysiol VL - 24 IS - 10 N2 - INTRODUCTION: Open-irrigated radiofrequency ablation catheters with slight differences in tip architecture are widely used, although limited comparative data are available. The purpose of this study was to compare the lesion size and potential complications produced by commercially available open-irrigated catheters in an in vitro porcine heart model. METHODS AND RESULTS: Six catheters were tested (Biosense Webster Thermocool, Boston Scientific Open irrigated, St. Jude CoolPath, St. Jude CoolPath Duo, Biosense Webster Thermocool SF, St. Jude Cool Flex) at 20 and 35 W power-control, under 2 different blood flows (0.1 and 0.5 m/s) and at 2 target durations (30 and 60 seconds). A total of 601 lesions were made in 26 in vitro preparations. The tip temperature profile showed significant differences between the catheters (P < 0.001) with the Thermocool SF registering the lowest. Only the surface diameter and the depth at maximum diameter of the lesion were influenced by the design of the ablation electrode. The lesion volume did not show significant differences between catheters for any power, application duration or blood flow condition. Char and pops occurred more often at 35 W with only slight differences between the catheters. CONCLUSIONS: Tip design of the 6 different irrigated catheters does not affect the lesion total volume, although a slight difference in lesion geometry in terms of surface diameter and depth at maximum diameter is present. The catheters show a slight different in vitro safety profile. SN - 1540-8167 UR - https://www.unboundmedicine.com/medline/citation/23718822/Effects_of_open_irrigated_radiofrequency_ablation_catheter_design_on_lesion_formation_and_complications:_in_vitro_comparison_of_6_different_devices_ L2 - https://doi.org/10.1111/jce.12175 DB - PRIME DP - Unbound Medicine ER -