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Anxiety, depression, quality of life and patient satisfaction in acne patients treated with oral isotretinoin.
Acta Derm Venereol. 2013 Nov; 93(6):701-6.AD

Abstract

Oral isotretinoin is effective in the clinical control of acne, but the relationship between this treatment and its psychosocial impact on the patient has not been completely clarified. The aim of this study was to determine if the use of oral isotretinoin in total accumulated doses of 120 mg/kg in a sample of 346 patients with moderate acne was useful in controlling symptoms of anxiety and/or depression and improving quality of life. A further objective was to ascertain the level of patient satisfaction with the treatment. After 30 weeks, there was a significant reduction in clinical symptoms (p < 0.001). The negative impact on quality of life, measured with the Dermatology Life Quality Index and the Health Survey Short-Form-36 (p < 0.001), showed a significant reduction, as did the Hospital Anxiety and Depression Scale scores for anxiety (p < 0.001) and depression (p < 0.005). At the end of the study, the mean level of patient satisfaction with improvement of symptoms was 84.4%.

Authors+Show Affiliations

Department of Dermatology, Alcañiz Hospital, ES-44600 Alcañiz, Spain.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Multicenter Study
Observational Study

Language

eng

PubMed ID

23727704

Citation

Marron, Servando E., et al. "Anxiety, Depression, Quality of Life and Patient Satisfaction in Acne Patients Treated With Oral Isotretinoin." Acta Dermato-venereologica, vol. 93, no. 6, 2013, pp. 701-6.
Marron SE, Tomas-Aragones L, Boira S. Anxiety, depression, quality of life and patient satisfaction in acne patients treated with oral isotretinoin. Acta Derm Venereol. 2013;93(6):701-6.
Marron, S. E., Tomas-Aragones, L., & Boira, S. (2013). Anxiety, depression, quality of life and patient satisfaction in acne patients treated with oral isotretinoin. Acta Dermato-venereologica, 93(6), 701-6. https://doi.org/10.2340/00015555-1638
Marron SE, Tomas-Aragones L, Boira S. Anxiety, Depression, Quality of Life and Patient Satisfaction in Acne Patients Treated With Oral Isotretinoin. Acta Derm Venereol. 2013;93(6):701-6. PubMed PMID: 23727704.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anxiety, depression, quality of life and patient satisfaction in acne patients treated with oral isotretinoin. AU - Marron,Servando E, AU - Tomas-Aragones,Lucia, AU - Boira,Santiago, PY - 2013/6/4/entrez PY - 2013/6/4/pubmed PY - 2014/6/19/medline SP - 701 EP - 6 JF - Acta dermato-venereologica JO - Acta Derm Venereol VL - 93 IS - 6 N2 - Oral isotretinoin is effective in the clinical control of acne, but the relationship between this treatment and its psychosocial impact on the patient has not been completely clarified. The aim of this study was to determine if the use of oral isotretinoin in total accumulated doses of 120 mg/kg in a sample of 346 patients with moderate acne was useful in controlling symptoms of anxiety and/or depression and improving quality of life. A further objective was to ascertain the level of patient satisfaction with the treatment. After 30 weeks, there was a significant reduction in clinical symptoms (p < 0.001). The negative impact on quality of life, measured with the Dermatology Life Quality Index and the Health Survey Short-Form-36 (p < 0.001), showed a significant reduction, as did the Hospital Anxiety and Depression Scale scores for anxiety (p < 0.001) and depression (p < 0.005). At the end of the study, the mean level of patient satisfaction with improvement of symptoms was 84.4%. SN - 1651-2057 UR - https://www.unboundmedicine.com/medline/citation/23727704/Anxiety_depression_quality_of_life_and_patient_satisfaction_in_acne_patients_treated_with_oral_isotretinoin_ L2 - https://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-1638 DB - PRIME DP - Unbound Medicine ER -