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Mesoscale modeling: solving complex flows in biology and biotechnology.
Trends Biotechnol 2013; 31(7):426-34TB

Abstract

Fluids are involved in practically all physiological activities of living organisms. However, biological and biorelated flows are hard to analyze due to the inherent combination of interdependent effects and processes that occur on a multitude of spatial and temporal scales. Recent advances in mesoscale simulations enable researchers to tackle problems that are central for the understanding of such flows. Furthermore, computational modeling effectively facilitates the development of novel therapeutic approaches. Among other methods, dissipative particle dynamics and the lattice Boltzmann method have become increasingly popular during recent years due to their ability to solve a large variety of problems. In this review, we discuss recent applications of these mesoscale methods to several fluid-related problems in medicine, bioengineering, and biotechnology.

Authors+Show Affiliations

George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

23755997

Citation

Mills, Zachary Grant, et al. "Mesoscale Modeling: Solving Complex Flows in Biology and Biotechnology." Trends in Biotechnology, vol. 31, no. 7, 2013, pp. 426-34.
Mills ZG, Mao W, Alexeev A. Mesoscale modeling: solving complex flows in biology and biotechnology. Trends Biotechnol. 2013;31(7):426-34.
Mills, Z. G., Mao, W., & Alexeev, A. (2013). Mesoscale modeling: solving complex flows in biology and biotechnology. Trends in Biotechnology, 31(7), pp. 426-34. doi:10.1016/j.tibtech.2013.05.001.
Mills ZG, Mao W, Alexeev A. Mesoscale Modeling: Solving Complex Flows in Biology and Biotechnology. Trends Biotechnol. 2013;31(7):426-34. PubMed PMID: 23755997.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mesoscale modeling: solving complex flows in biology and biotechnology. AU - Mills,Zachary Grant, AU - Mao,Wenbin, AU - Alexeev,Alexander, Y1 - 2013/06/04/ PY - 2013/01/29/received PY - 2013/05/03/revised PY - 2013/05/04/accepted PY - 2013/6/13/entrez PY - 2013/6/13/pubmed PY - 2014/1/3/medline SP - 426 EP - 34 JF - Trends in biotechnology JO - Trends Biotechnol. VL - 31 IS - 7 N2 - Fluids are involved in practically all physiological activities of living organisms. However, biological and biorelated flows are hard to analyze due to the inherent combination of interdependent effects and processes that occur on a multitude of spatial and temporal scales. Recent advances in mesoscale simulations enable researchers to tackle problems that are central for the understanding of such flows. Furthermore, computational modeling effectively facilitates the development of novel therapeutic approaches. Among other methods, dissipative particle dynamics and the lattice Boltzmann method have become increasingly popular during recent years due to their ability to solve a large variety of problems. In this review, we discuss recent applications of these mesoscale methods to several fluid-related problems in medicine, bioengineering, and biotechnology. SN - 1879-3096 UR - https://www.unboundmedicine.com/medline/citation/23755997/Mesoscale_modeling:_solving_complex_flows_in_biology_and_biotechnology_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0167-7799(13)00095-4 DB - PRIME DP - Unbound Medicine ER -