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Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France.
Arch Virol. 2013 Nov; 158(11):2333-40.AV

Abstract

Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by whole-genome sequencing and compared to that of the first BBLV strain isolated in 2010 in Germany and with those of all currently identified lyssaviruses. The French isolate [KC169985] showed 98.7 % nucleotide sequence identity to the German BBLV strain [JF311903]. Several organs of the infected French bat were examined by classical rabies diagnostic methods: fluorescent antibody test, cell culture inoculation test and RT-qPCR. Antigen, infectious virus and high viral RNA levels were found in both the brain and salivary glands. Traces of genomic RNA were detected in the bladder, kidney and lung tissue. The results of an investigation of the distribution of lyssaviruses with the detection of infectious virus in the salivary glands suggest a possible mode of transmission of the virus.

Authors+Show Affiliations

Anses, Laboratory for Rabies and Wildlife, European Union Reference Laboratory for rabies, European Union Reference Laboratory for rabies serology, OIE Reference Laboratory for rabies, WHO Collaborating centre for research and management in zoonoses control, Technopole agricole et veterinaire, BP 40009, 54 220, Malzéville Cedex, France, evelyne.picard-meyer@anses.fr.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23760600

Citation

Picard-Meyer, Evelyne, et al. "Isolation of Bokeloh Bat Lyssavirus in Myotis Nattereri in France." Archives of Virology, vol. 158, no. 11, 2013, pp. 2333-40.
Picard-Meyer E, Servat A, Robardet E, et al. Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France. Arch Virol. 2013;158(11):2333-40.
Picard-Meyer, E., Servat, A., Robardet, E., Moinet, M., Borel, C., & Cliquet, F. (2013). Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France. Archives of Virology, 158(11), 2333-40. https://doi.org/10.1007/s00705-013-1747-y
Picard-Meyer E, et al. Isolation of Bokeloh Bat Lyssavirus in Myotis Nattereri in France. Arch Virol. 2013;158(11):2333-40. PubMed PMID: 23760600.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Isolation of Bokeloh bat lyssavirus in Myotis nattereri in France. AU - Picard-Meyer,Evelyne, AU - Servat,Alexandre, AU - Robardet,Emmanuelle, AU - Moinet,Marie, AU - Borel,Christophe, AU - Cliquet,Florence, Y1 - 2013/06/12/ PY - 2013/03/25/received PY - 2013/04/25/accepted PY - 2013/6/14/entrez PY - 2013/6/14/pubmed PY - 2014/1/7/medline SP - 2333 EP - 40 JF - Archives of virology JO - Arch Virol VL - 158 IS - 11 N2 - Bokeloh bat lyssavirus (BBLV) was found in Myotis nattereri for the first time in northeastern France in July 2012. The complete genome sequence of the virus from the infected Natterer's bat was determined by whole-genome sequencing and compared to that of the first BBLV strain isolated in 2010 in Germany and with those of all currently identified lyssaviruses. The French isolate [KC169985] showed 98.7 % nucleotide sequence identity to the German BBLV strain [JF311903]. Several organs of the infected French bat were examined by classical rabies diagnostic methods: fluorescent antibody test, cell culture inoculation test and RT-qPCR. Antigen, infectious virus and high viral RNA levels were found in both the brain and salivary glands. Traces of genomic RNA were detected in the bladder, kidney and lung tissue. The results of an investigation of the distribution of lyssaviruses with the detection of infectious virus in the salivary glands suggest a possible mode of transmission of the virus. SN - 1432-8798 UR - https://www.unboundmedicine.com/medline/citation/23760600/Isolation_of_Bokeloh_bat_lyssavirus_in_Myotis_nattereri_in_France_ L2 - https://dx.doi.org/10.1007/s00705-013-1747-y DB - PRIME DP - Unbound Medicine ER -