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Cerebral toxoplasmosis in systemic lupus erythematosus following intravenous methylprednisolone.

Abstract

Cerebral toxoplasmosis is a rare complication of systemic lupus erythematosus (SLE). An 18 year old male student, newly diagnosed to have SLE, developed neurological symptoms two days after completing intravenous methylprednisolone. Computed tomography (CT) scan showed features consistent with a diagnosis of probable cerebral toxoplasmosis. He responded dramatically to antitoxoplasma therapy. To our knowledge, this is the first case report in the literature that presents a newly diagnosed SLE patient who rapidly developed cerebral toxoplasmosis following administration of intravenous methylprednisolone. Our case illustrates that this drug is potentially fatal and the importance of differentiating cerebral infection from neuropsychiatric lupus.

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  • Authors+Show Affiliations

    ,

    Columbia Asia Hospital Nusajaya, Persiaraan Afiat, Taman Kesihatan Afiat, 79250 Nusajay Malaysia. pagal72@gmail.com.

    Source

    The Medical journal of Malaysia 66:1 2011 Mar pg 68-70

    MeSH

    Humans
    Lupus Erythematosus, Systemic
    Methylprednisolone
    Toxoplasmosis, Cerebral

    Pub Type(s)

    Case Reports
    Journal Article

    Language

    eng

    PubMed ID

    23765150

    Citation

    Pagalavan, L, and F K. Kan. "Cerebral Toxoplasmosis in Systemic Lupus Erythematosus Following Intravenous Methylprednisolone." The Medical Journal of Malaysia, vol. 66, no. 1, 2011, pp. 68-70.
    Pagalavan L, Kan FK. Cerebral toxoplasmosis in systemic lupus erythematosus following intravenous methylprednisolone. Med J Malaysia. 2011;66(1):68-70.
    Pagalavan, L., & Kan, F. K. (2011). Cerebral toxoplasmosis in systemic lupus erythematosus following intravenous methylprednisolone. The Medical Journal of Malaysia, 66(1), pp. 68-70.
    Pagalavan L, Kan FK. Cerebral Toxoplasmosis in Systemic Lupus Erythematosus Following Intravenous Methylprednisolone. Med J Malaysia. 2011;66(1):68-70. PubMed PMID: 23765150.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Cerebral toxoplasmosis in systemic lupus erythematosus following intravenous methylprednisolone. AU - Pagalavan,L, AU - Kan,F K, PY - 2013/6/15/entrez PY - 2011/3/1/pubmed PY - 2016/4/24/medline SP - 68 EP - 70 JF - The Medical journal of Malaysia JO - Med. J. Malaysia VL - 66 IS - 1 N2 - Cerebral toxoplasmosis is a rare complication of systemic lupus erythematosus (SLE). An 18 year old male student, newly diagnosed to have SLE, developed neurological symptoms two days after completing intravenous methylprednisolone. Computed tomography (CT) scan showed features consistent with a diagnosis of probable cerebral toxoplasmosis. He responded dramatically to antitoxoplasma therapy. To our knowledge, this is the first case report in the literature that presents a newly diagnosed SLE patient who rapidly developed cerebral toxoplasmosis following administration of intravenous methylprednisolone. Our case illustrates that this drug is potentially fatal and the importance of differentiating cerebral infection from neuropsychiatric lupus. SN - 0300-5283 UR - https://www.unboundmedicine.com/medline/citation/23765150/Cerebral_toxoplasmosis_in_systemic_lupus_erythematosus_following_intravenous_methylprednisolone_ L2 - http://www.e-mjm.org/2011/v66n1/Systemic_lupus_erythematosus.pdf DB - PRIME DP - Unbound Medicine ER -