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Cronkhite-Canada syndrome associated with serrated adenoma and malignant polyp: a case report and a literature review of 13 cronkhite-Canada syndrome cases in Korea.
Clin Endosc. 2013 May; 46(3):301-5.CE

Abstract

Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances both in the gastrointestinal tract and in the epidermis. The pathologic finding of the polyp is usually a hamartomatous polyp of the juvenile type; however, the possibility of serrated adenoma associated malignant neoplasm was reported in some Japanese cases. Up till now in South Korea, 13 CCS cases have been reported, but there was no case accompanied by the colon cancer. We report the first case of CCS associated with malignant colon polyp and serrated adenoma in Korea. A 72-year-old male patient who complained of diarrhea and weight loss was presented with both hands and feet nail dystrophy, hyperpigmentation, and alopecia. Endoscopic examination showed numerous hamartomatous polyps from the stomach to the colon. The pathologic results confirmed colon cancer and serrated adenoma. Helicobacter pylori eradication and prednisolone was used. Thus, the authors report this case along with a literature review.

Authors+Show Affiliations

Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23767045

Citation

Yun, So Hee, et al. "Cronkhite-Canada Syndrome Associated With Serrated Adenoma and Malignant Polyp: a Case Report and a Literature Review of 13 cronkhite-Canada Syndrome Cases in Korea." Clinical Endoscopy, vol. 46, no. 3, 2013, pp. 301-5.
Yun SH, Cho JW, Kim JW, et al. Cronkhite-Canada syndrome associated with serrated adenoma and malignant polyp: a case report and a literature review of 13 cronkhite-Canada syndrome cases in Korea. Clin Endosc. 2013;46(3):301-5.
Yun, S. H., Cho, J. W., Kim, J. W., Kim, J. K., Park, M. S., Lee, N. E., Lee, J. U., & Lee, Y. J. (2013). Cronkhite-Canada syndrome associated with serrated adenoma and malignant polyp: a case report and a literature review of 13 cronkhite-Canada syndrome cases in Korea. Clinical Endoscopy, 46(3), 301-5. https://doi.org/10.5946/ce.2013.46.3.301
Yun SH, et al. Cronkhite-Canada Syndrome Associated With Serrated Adenoma and Malignant Polyp: a Case Report and a Literature Review of 13 cronkhite-Canada Syndrome Cases in Korea. Clin Endosc. 2013;46(3):301-5. PubMed PMID: 23767045.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cronkhite-Canada syndrome associated with serrated adenoma and malignant polyp: a case report and a literature review of 13 cronkhite-Canada syndrome cases in Korea. AU - Yun,So Hee, AU - Cho,Jin Woong, AU - Kim,Ji Woong, AU - Kim,Joong Keun, AU - Park,Moon Sik, AU - Lee,Na Eun, AU - Lee,Jae Un, AU - Lee,Young Jae, Y1 - 2013/05/31/ PY - 2012/06/26/received PY - 2012/09/03/revised PY - 2012/09/05/accepted PY - 2013/6/15/entrez PY - 2013/6/15/pubmed PY - 2013/6/15/medline KW - Colonic neoplasms KW - Helicobacter pylori KW - Intestinal polyposis KW - Serrated adenoma SP - 301 EP - 5 JF - Clinical endoscopy JO - Clin Endosc VL - 46 IS - 3 N2 - Cronkhite-Canada syndrome (CCS) is a rare nonfamilial polyposis syndrome characterized by epithelial disturbances both in the gastrointestinal tract and in the epidermis. The pathologic finding of the polyp is usually a hamartomatous polyp of the juvenile type; however, the possibility of serrated adenoma associated malignant neoplasm was reported in some Japanese cases. Up till now in South Korea, 13 CCS cases have been reported, but there was no case accompanied by the colon cancer. We report the first case of CCS associated with malignant colon polyp and serrated adenoma in Korea. A 72-year-old male patient who complained of diarrhea and weight loss was presented with both hands and feet nail dystrophy, hyperpigmentation, and alopecia. Endoscopic examination showed numerous hamartomatous polyps from the stomach to the colon. The pathologic results confirmed colon cancer and serrated adenoma. Helicobacter pylori eradication and prednisolone was used. Thus, the authors report this case along with a literature review. SN - 2234-2400 UR - https://www.unboundmedicine.com/medline/citation/23767045/Cronkhite_Canada_syndrome_associated_with_serrated_adenoma_and_malignant_polyp:_a_case_report_and_a_literature_review_of_13_cronkhite_Canada_syndrome_cases_in_Korea_ L2 - https://dx.doi.org/10.5946/ce.2013.46.3.301 DB - PRIME DP - Unbound Medicine ER -
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