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Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly.

Abstract

COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95% CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD.

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  • Authors+Show Affiliations

    ,

    Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Medical University Hospital, Taiwan. chenling@tmu.edu.tw

    , , , ,

    Source

    MeSH

    Adolescent
    Adult
    Aged
    Aged, 80 and over
    Child
    Child, Preschool
    Cohort Studies
    Computer Systems
    Data Collection
    Databases, Factual
    Female
    Humans
    Infant
    Influenza Vaccines
    Influenza, Human
    Male
    Middle Aged
    Myocardial Ischemia
    Pulmonary Disease, Chronic Obstructive
    Risk
    Software
    Taiwan
    Treatment Outcome
    Young Adult

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    23769164

    Citation

    Huang, Chen-Ling, et al. "Influenza Vaccination and Reduction in Risk of Ischemic Heart Disease Among Chronic Obstructive Pulmonary Elderly." Computer Methods and Programs in Biomedicine, vol. 111, no. 2, 2013, pp. 507-11.
    Huang CL, Nguyen PA, Kuo PL, et al. Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly. Comput Methods Programs Biomed. 2013;111(2):507-11.
    Huang, C. L., Nguyen, P. A., Kuo, P. L., Iqbal, U., Hsu, Y. H., & Jian, W. S. (2013). Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly. Computer Methods and Programs in Biomedicine, 111(2), pp. 507-11. doi:10.1016/j.cmpb.2013.05.006.
    Huang CL, et al. Influenza Vaccination and Reduction in Risk of Ischemic Heart Disease Among Chronic Obstructive Pulmonary Elderly. Comput Methods Programs Biomed. 2013;111(2):507-11. PubMed PMID: 23769164.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Influenza vaccination and reduction in risk of ischemic heart disease among chronic obstructive pulmonary elderly. AU - Huang,Chen-Ling, AU - Nguyen,Phung Anh, AU - Kuo,Pih-lian, AU - Iqbal,Usman, AU - Hsu,Yi-Hsin Elsa, AU - Jian,Wen-Shan, Y1 - 2013/06/12/ PY - 2013/03/08/received PY - 2013/04/22/revised PY - 2013/05/15/accepted PY - 2013/6/18/entrez PY - 2013/6/19/pubmed PY - 2014/2/12/medline KW - COPD (chronic obstructive pulmonary disease) KW - Cohort research database KW - IHD (ischemic heart disease) KW - Influenza vaccine KW - Vaccination SP - 507 EP - 11 JF - Computer methods and programs in biomedicine JO - Comput Methods Programs Biomed VL - 111 IS - 2 N2 - COPD estimates the third leading cause of death by 2020. To reduce its complications becomes an important issue. The purpose of this study is to investigate the influenza vaccine effect for IHD occurrence with secondary to COPD. We used 11 years Taiwan National Health Insurance cohort research database and analyzed the relationships between vaccination and incident of IHD for COPD patients stratified by age. Total 29,178 COPD patients, 703 patients got vaccination out of 1464 who have developed IHD and 6010 patients vaccinated out of 27,714 that did not developed IHD. Major findings we observed: vaccination was associated with a reduced risk of IHD (OR, 0.746; 95% CI, 0.595-0.937) in elderly COPD patients. Influenza vaccination was associated with a reduced risk for IHD only in elderly COPD patients. Moreover, COPD patients with IHD had higher vaccination rate than without IHD. SN - 1872-7565 UR - https://www.unboundmedicine.com/medline/citation/23769164/Influenza_vaccination_and_reduction_in_risk_of_ischemic_heart_disease_among_chronic_obstructive_pulmonary_elderly_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0169-2607(13)00163-6 DB - PRIME DP - Unbound Medicine ER -