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Seroprevalence of measles, mumps and rubella among children in American Samoa, 2011, and progress towards West Pacific Region goals of elimination.
Vaccine. 2013 Aug 12; 31(36):3683-7.V

Abstract

INTRODUCTION

In line with the global goals for measles elimination, countries in the West Pacific Region (WPR) have set a goal to eliminate measles by 2012. Due to its contagiousness, high population immunity is needed for achieving and documenting measles elimination. We assessed population immunity to measles, mumps and rubella among first grade children in American Samoa (AS) through a seroprevalance study.

METHODS

Using commercial indirect enzyme-linked immunosorbant IgG assays (Wampole Laboratories, Cranbury, NJ) we determined IgG antibodies against the measles, mumps, and rubella (MMR) viruses in sera collected from first grade students in AS in April-May 2011. Vaccination status was retrieved from the immunization cards. Factors associated with seropositivity of measles, mumps, and rubella were analyzed separately.

RESULT

Among 509 first grade students, measles, mumps, and rubella seroprevalence were 92%, 90%, and 93%, respectively. The proportions of first grade students with documented one or two doses of MMR vaccine were 93% and 84%, respectively. The vaccination status of 6% of the first graders was unknown and 1% was unvaccinated. Receiving two-doses of MMR vaccines was associated with high measles and mumps seropositivity (p<0.01).

CONCLUSION

The high measles seroprevalence among children shows the progress by American Samoa towards measles elimination. Achieving and maintaining high two-dose MMR vaccine coverage in all age groups will aid in attaining the measles elimination status and prevent transmission of measles from potential imported measles cases from other countries.

Authors+Show Affiliations

National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA. Amahamud@cdc.govNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

23770334

Citation

Mahamud, Abdirahman, et al. "Seroprevalence of Measles, Mumps and Rubella Among Children in American Samoa, 2011, and Progress Towards West Pacific Region Goals of Elimination." Vaccine, vol. 31, no. 36, 2013, pp. 3683-7.
Mahamud A, Masunu-Faleafaga Y, Walls L, et al. Seroprevalence of measles, mumps and rubella among children in American Samoa, 2011, and progress towards West Pacific Region goals of elimination. Vaccine. 2013;31(36):3683-7.
Mahamud, A., Masunu-Faleafaga, Y., Walls, L., Williams, N., Garcia, P., Teshale, E., Williams, R., Dulski, T., Bellini, W. J., & Kutty, P. K. (2013). Seroprevalence of measles, mumps and rubella among children in American Samoa, 2011, and progress towards West Pacific Region goals of elimination. Vaccine, 31(36), 3683-7. https://doi.org/10.1016/j.vaccine.2013.05.102
Mahamud A, et al. Seroprevalence of Measles, Mumps and Rubella Among Children in American Samoa, 2011, and Progress Towards West Pacific Region Goals of Elimination. Vaccine. 2013 Aug 12;31(36):3683-7. PubMed PMID: 23770334.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of measles, mumps and rubella among children in American Samoa, 2011, and progress towards West Pacific Region goals of elimination. AU - Mahamud,Abdirahman, AU - Masunu-Faleafaga,Yolanda, AU - Walls,Laura, AU - Williams,Nobia, AU - Garcia,Philip, AU - Teshale,Eyasu, AU - Williams,Roxanne, AU - Dulski,Theresa, AU - Bellini,William J, AU - Kutty,Preeta K, Y1 - 2013/06/13/ PY - 2013/02/25/received PY - 2013/05/15/revised PY - 2013/05/30/accepted PY - 2013/6/18/entrez PY - 2013/6/19/pubmed PY - 2014/5/23/medline KW - ACIP KW - AS KW - ASDOE KW - ASDOH KW - Advisory Committee for Immunization Practices KW - American Samoa KW - American Samoa Department of Health KW - CDC KW - Centers for Disease Control and Prevention KW - Department of Education KW - MMR vaccine KW - Measles KW - Mumps KW - Rubella KW - Seroprevalence KW - measles–mumps–rubella vaccine SP - 3683 EP - 7 JF - Vaccine JO - Vaccine VL - 31 IS - 36 N2 - INTRODUCTION: In line with the global goals for measles elimination, countries in the West Pacific Region (WPR) have set a goal to eliminate measles by 2012. Due to its contagiousness, high population immunity is needed for achieving and documenting measles elimination. We assessed population immunity to measles, mumps and rubella among first grade children in American Samoa (AS) through a seroprevalance study. METHODS: Using commercial indirect enzyme-linked immunosorbant IgG assays (Wampole Laboratories, Cranbury, NJ) we determined IgG antibodies against the measles, mumps, and rubella (MMR) viruses in sera collected from first grade students in AS in April-May 2011. Vaccination status was retrieved from the immunization cards. Factors associated with seropositivity of measles, mumps, and rubella were analyzed separately. RESULT: Among 509 first grade students, measles, mumps, and rubella seroprevalence were 92%, 90%, and 93%, respectively. The proportions of first grade students with documented one or two doses of MMR vaccine were 93% and 84%, respectively. The vaccination status of 6% of the first graders was unknown and 1% was unvaccinated. Receiving two-doses of MMR vaccines was associated with high measles and mumps seropositivity (p<0.01). CONCLUSION: The high measles seroprevalence among children shows the progress by American Samoa towards measles elimination. Achieving and maintaining high two-dose MMR vaccine coverage in all age groups will aid in attaining the measles elimination status and prevent transmission of measles from potential imported measles cases from other countries. SN - 1873-2518 UR - https://www.unboundmedicine.com/medline/citation/23770334/Seroprevalence_of_measles_mumps_and_rubella_among_children_in_American_Samoa_2011_and_progress_towards_West_Pacific_Region_goals_of_elimination_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0264-410X(13)00762-7 DB - PRIME DP - Unbound Medicine ER -