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Synthesis of polysubstituted furans via copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids.
Org Lett. 2013 Jul 05; 15(13):3206-9.OL

Abstract

A novel copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids has been accomplished. This reaction provides a facile and regio-defined method for the synthesis of 2,3,5-trisubstituted furans from simple chemical reagents.

Authors+Show Affiliations

Department of Chemistry, ZJU-NHU United R&D Center, Zhejiang University, Hangzhou 310027, P. R. China.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23772562

Citation

Yang, Yuzhu, et al. "Synthesis of Polysubstituted Furans Via Copper-mediated Annulation of Alkyl Ketones With Α,β-unsaturated Carboxylic Acids." Organic Letters, vol. 15, no. 13, 2013, pp. 3206-9.
Yang Y, Yao J, Zhang Y. Synthesis of polysubstituted furans via copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids. Org Lett. 2013;15(13):3206-9.
Yang, Y., Yao, J., & Zhang, Y. (2013). Synthesis of polysubstituted furans via copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids. Organic Letters, 15(13), 3206-9. https://doi.org/10.1021/ol400912v
Yang Y, Yao J, Zhang Y. Synthesis of Polysubstituted Furans Via Copper-mediated Annulation of Alkyl Ketones With Α,β-unsaturated Carboxylic Acids. Org Lett. 2013 Jul 5;15(13):3206-9. PubMed PMID: 23772562.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Synthesis of polysubstituted furans via copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids. AU - Yang,Yuzhu, AU - Yao,Jinzhong, AU - Zhang,Yuhong, Y1 - 2013/06/17/ PY - 2013/6/19/entrez PY - 2013/6/19/pubmed PY - 2014/1/9/medline SP - 3206 EP - 9 JF - Organic letters JO - Org. Lett. VL - 15 IS - 13 N2 - A novel copper-mediated annulation of alkyl ketones with α,β-unsaturated carboxylic acids has been accomplished. This reaction provides a facile and regio-defined method for the synthesis of 2,3,5-trisubstituted furans from simple chemical reagents. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/23772562/Synthesis_of_polysubstituted_furans_via_copper_mediated_annulation_of_alkyl_ketones_with_αβ_unsaturated_carboxylic_acids_ L2 - https://dx.doi.org/10.1021/ol400912v DB - PRIME DP - Unbound Medicine ER -