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Opinion: Perspectives on imaging in axial spondyloarthritis.
Nat Rev Rheumatol 2013; 9(8):498-502NR

Abstract

The diagnosis of axial spondyloarthritis (axSpA) is based on detection of characteristic inflammatory or structural changes (or a combination of both) in the spine and sacroiliac joints. Imaging of the axial skeleton is, therefore, useful for the identification of these pathological changes. Both inflammation (best detected by MRI) and bone formation (best visualized by conventional radiography) can predict the development of future structural changes. In addition, a high degree of spinal inflammation on MRI is predictive of a successful response to anti-TNF therapy. Emerging data indicate that the combination of acute and chronic changes on MRI has an important influence on progression of nonradiographic axSpA to ankylosing spondylitis. This Perspectives article provides an overview of the role of imaging in the diagnosis and management of axSpA, and also discusses open questions and future perspectives in this field.

Authors+Show Affiliations

Rheumazentrum Ruhrgebiet Herne, Ruhr-University Bochum, Landgrafenstrasse 15, 44652 Herne, Germany. baraliakos@me.comNo affiliation info available

Pub Type(s)

Review

Language

eng

PubMed ID

23774899

Citation

Baraliakos, Xenofon, and Jürgen Braun. "Opinion: Perspectives On Imaging in Axial Spondyloarthritis." Nature Reviews. Rheumatology, vol. 9, no. 8, 2013, pp. 498-502.
Baraliakos X, Braun J. Opinion: Perspectives on imaging in axial spondyloarthritis. Nat Rev Rheumatol. 2013;9(8):498-502.
Baraliakos, X., & Braun, J. (2013). Opinion: Perspectives on imaging in axial spondyloarthritis. Nature Reviews. Rheumatology, 9(8), pp. 498-502. doi:10.1038/nrrheum.2013.83.
Baraliakos X, Braun J. Opinion: Perspectives On Imaging in Axial Spondyloarthritis. Nat Rev Rheumatol. 2013;9(8):498-502. PubMed PMID: 23774899.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Opinion: Perspectives on imaging in axial spondyloarthritis. AU - Baraliakos,Xenofon, AU - Braun,Jürgen, Y1 - 2013/06/18/ PY - 2013/6/19/entrez PY - 2013/6/19/pubmed PY - 2014/2/28/medline SP - 498 EP - 502 JF - Nature reviews. Rheumatology JO - Nat Rev Rheumatol VL - 9 IS - 8 N2 - The diagnosis of axial spondyloarthritis (axSpA) is based on detection of characteristic inflammatory or structural changes (or a combination of both) in the spine and sacroiliac joints. Imaging of the axial skeleton is, therefore, useful for the identification of these pathological changes. Both inflammation (best detected by MRI) and bone formation (best visualized by conventional radiography) can predict the development of future structural changes. In addition, a high degree of spinal inflammation on MRI is predictive of a successful response to anti-TNF therapy. Emerging data indicate that the combination of acute and chronic changes on MRI has an important influence on progression of nonradiographic axSpA to ankylosing spondylitis. This Perspectives article provides an overview of the role of imaging in the diagnosis and management of axSpA, and also discusses open questions and future perspectives in this field. SN - 1759-4804 UR - https://www.unboundmedicine.com/medline/citation/23774899/Opinion:_Perspectives_on_imaging_in_axial_spondyloarthritis_ L2 - http://dx.doi.org/10.1038/nrrheum.2013.83 DB - PRIME DP - Unbound Medicine ER -