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Differences in prenatal exposure to mercury in South African communities residing along the Indian Ocean.
Sci Total Environ. 2013 Oct 01; 463-464:11-9.ST

Abstract

Mercury is a persistent environmental pollutant that has the potential to adversely affect human health, particularly, foetal neurodevelopment. The purpose of the study was to investigate prenatal mercury (Hg) exposure in the population in three sites along the South Africa coast. Study subjects included women (n=350) who were admitted for delivery at the local hospitals. Maternal and cord blood samples were collected to measure total mercury and each participant was required to answer a questionnaire. The 90th percentile of mercury levels in maternal and cord blood of the total population was 1.15 μg/l and 1.67 μg/l, respectively. Site 1 (Manguzi) participants had the highest maternal geometric mean (GM) values of 0.93 μg/l, which was significantly different from Site 2 (Port Shepstone) (0.49 μg/l) and Site 3 (Empangeni) (0.56 μg/l) (ANOVA test, p<0.001). Umbilical cord blood GM Hg level for Site 1 (1.45 μg/l) was more than double the GM Hg level in Site 2 (0.70 μg/l) and Site 3 (0.73 μg/l). Univariate analysis indicated that the following maternal characteristics were positive predictors for elevated umbilical cord Hg levels: maternal blood Hg levels, living with a partner, residing in Site 1, living in informal housing, using wood and gas for cooking, borehole water as a drinking source, and a member of the household being involved in fishing. Maternal dietary predictors of elevated Hg levels in umbilical cord blood included consuming fresh fish, tinned fish, fruit or dairy products, daily. This study provides baseline data and reveals that 2% of the study population were above the EPA's reference value (5.8 μg/l) suggesting low level exposure to mercury in pregnant women and the developing foetus in South Africa. Further research is required to explore the sources of elevated Hg levels in Site 1.

Authors+Show Affiliations

Institute of Community Medicine, University of Tromsø, Tromsø, Norway; National Health Laboratory Service (NHLS), National Institute for Occupational Health (NIOH), Johannesburg, South Africa. Electronic address: Kalavati.Channa@nioh.nhls.ac.za.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

23787104

Citation

Channa, Kalavati, et al. "Differences in Prenatal Exposure to Mercury in South African Communities Residing Along the Indian Ocean." The Science of the Total Environment, vol. 463-464, 2013, pp. 11-9.
Channa K, Odland JØ, Kootbodien T, et al. Differences in prenatal exposure to mercury in South African communities residing along the Indian Ocean. Sci Total Environ. 2013;463-464:11-9.
Channa, K., Odland, J. Ø., Kootbodien, T., Theodorou, P., Naik, I., Sandanger, T. M., & Röllin, H. B. (2013). Differences in prenatal exposure to mercury in South African communities residing along the Indian Ocean. The Science of the Total Environment, 463-464, 11-9. https://doi.org/10.1016/j.scitotenv.2013.05.055
Channa K, et al. Differences in Prenatal Exposure to Mercury in South African Communities Residing Along the Indian Ocean. Sci Total Environ. 2013 Oct 1;463-464:11-9. PubMed PMID: 23787104.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Differences in prenatal exposure to mercury in South African communities residing along the Indian Ocean. AU - Channa,Kalavati, AU - Odland,Jon Ø, AU - Kootbodien,Tahira, AU - Theodorou,Penny, AU - Naik,Inakshi, AU - Sandanger,Torkjel M, AU - Röllin,Halina B, Y1 - 2013/06/17/ PY - 2013/02/08/received PY - 2013/05/13/revised PY - 2013/05/18/accepted PY - 2013/6/22/entrez PY - 2013/6/22/pubmed PY - 2014/4/15/medline KW - Africa KW - Cord-blood KW - Fish KW - Maternal KW - Mercury KW - Pregnant SP - 11 EP - 9 JF - The Science of the total environment JO - Sci Total Environ VL - 463-464 N2 - Mercury is a persistent environmental pollutant that has the potential to adversely affect human health, particularly, foetal neurodevelopment. The purpose of the study was to investigate prenatal mercury (Hg) exposure in the population in three sites along the South Africa coast. Study subjects included women (n=350) who were admitted for delivery at the local hospitals. Maternal and cord blood samples were collected to measure total mercury and each participant was required to answer a questionnaire. The 90th percentile of mercury levels in maternal and cord blood of the total population was 1.15 μg/l and 1.67 μg/l, respectively. Site 1 (Manguzi) participants had the highest maternal geometric mean (GM) values of 0.93 μg/l, which was significantly different from Site 2 (Port Shepstone) (0.49 μg/l) and Site 3 (Empangeni) (0.56 μg/l) (ANOVA test, p<0.001). Umbilical cord blood GM Hg level for Site 1 (1.45 μg/l) was more than double the GM Hg level in Site 2 (0.70 μg/l) and Site 3 (0.73 μg/l). Univariate analysis indicated that the following maternal characteristics were positive predictors for elevated umbilical cord Hg levels: maternal blood Hg levels, living with a partner, residing in Site 1, living in informal housing, using wood and gas for cooking, borehole water as a drinking source, and a member of the household being involved in fishing. Maternal dietary predictors of elevated Hg levels in umbilical cord blood included consuming fresh fish, tinned fish, fruit or dairy products, daily. This study provides baseline data and reveals that 2% of the study population were above the EPA's reference value (5.8 μg/l) suggesting low level exposure to mercury in pregnant women and the developing foetus in South Africa. Further research is required to explore the sources of elevated Hg levels in Site 1. SN - 1879-1026 UR - https://www.unboundmedicine.com/medline/citation/23787104/Differences_in_prenatal_exposure_to_mercury_in_South_African_communities_residing_along_the_Indian_Ocean_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0048-9697(13)00598-6 DB - PRIME DP - Unbound Medicine ER -