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[Effects of heptapeptide of the tuftsin group with nootropic components of action and piracetam on formation of escape reaction in normal conditions and in conflict situation].
Biull Eksp Biol Med. 1990 May; 109(5):445-6.BE

Abstract

In this work we have compared the effect of Tuftsin Group synthetic heptapeptide (TP-1) and Piracetam on learning of avoidance response and its restoring after disturbance provoked by unexpected changes of previously established cause-effect relations in experimental environment. We have pointed out that both of the drugs improve learning but the dynamics is different, namely: Piracetam causes the greatest improvement on the 1st day, meanwhile the Heptapeptide--on the 4th day. Both of them preclude from disturbing avoidance response and this protective action of peptide is more effective.

Authors

Inozemtsev AN
No affiliation info available
Kokaeva FF
No affiliation info available
Kozlovskiĭ II
No affiliation info available
Sarychev EI
No affiliation info available
Demidov VM
No affiliation info available
Tushmalova NA
No affiliation info available

MeSH

AnimalsAvoidance LearningConflict, PsychologicalEscape ReactionMalePiracetamPyrrolidinonesRatsTime FactorsTuftsin

Pub Type(s)

Comparative Study
Journal Article

Language

rus

PubMed ID

2378951

Citation

Inozemtsev, A N., et al. "[Effects of Heptapeptide of the Tuftsin Group With Nootropic Components of Action and Piracetam On Formation of Escape Reaction in Normal Conditions and in Conflict Situation]." Biulleten' Eksperimental'noi Biologii I Meditsiny, vol. 109, no. 5, 1990, pp. 445-6.
Inozemtsev AN, Kokaeva FF, Kozlovskiĭ II, et al. [Effects of heptapeptide of the tuftsin group with nootropic components of action and piracetam on formation of escape reaction in normal conditions and in conflict situation]. Biull Eksp Biol Med. 1990;109(5):445-6.
Inozemtsev, A. N., Kokaeva, F. F., Kozlovskiĭ, I. I., Sarychev, E. I., Demidov, V. M., & Tushmalova, N. A. (1990). [Effects of heptapeptide of the tuftsin group with nootropic components of action and piracetam on formation of escape reaction in normal conditions and in conflict situation]. Biulleten' Eksperimental'noi Biologii I Meditsiny, 109(5), 445-6.
Inozemtsev AN, et al. [Effects of Heptapeptide of the Tuftsin Group With Nootropic Components of Action and Piracetam On Formation of Escape Reaction in Normal Conditions and in Conflict Situation]. Biull Eksp Biol Med. 1990;109(5):445-6. PubMed PMID: 2378951.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effects of heptapeptide of the tuftsin group with nootropic components of action and piracetam on formation of escape reaction in normal conditions and in conflict situation]. AU - Inozemtsev,A N, AU - Kokaeva,F F, AU - Kozlovskiĭ,I I, AU - Sarychev,E I, AU - Demidov,V M, AU - Tushmalova,N A, PY - 1990/5/1/pubmed PY - 1990/5/1/medline PY - 1990/5/1/entrez SP - 445 EP - 6 JF - Biulleten' eksperimental'noi biologii i meditsiny JO - Biull Eksp Biol Med VL - 109 IS - 5 N2 - In this work we have compared the effect of Tuftsin Group synthetic heptapeptide (TP-1) and Piracetam on learning of avoidance response and its restoring after disturbance provoked by unexpected changes of previously established cause-effect relations in experimental environment. We have pointed out that both of the drugs improve learning but the dynamics is different, namely: Piracetam causes the greatest improvement on the 1st day, meanwhile the Heptapeptide--on the 4th day. Both of them preclude from disturbing avoidance response and this protective action of peptide is more effective. SN - 0365-9615 UR - https://www.unboundmedicine.com/medline/citation/2378951/[Effects_of_heptapeptide_of_the_tuftsin_group_with_nootropic_components_of_action_and_piracetam_on_formation_of_escape_reaction_in_normal_conditions_and_in_conflict_situation]_ DB - PRIME DP - Unbound Medicine ER -