TY - JOUR T1 - Quantitative microbiology of the scalp in non-dandruff, dandruff, and seborrheic dermatitis. AU - McGinley,K J, AU - Leyden,J J, AU - Marples,R R, AU - Kligman,A M, PY - 1975/6/1/pubmed PY - 1975/6/1/medline PY - 1975/6/1/entrez SP - 401 EP - 5 JF - The Journal of investigative dermatology JO - J Invest Dermatol VL - 64 IS - 6 N2 - The composition of the scalp microflora was assessed quantitatively in normal individuals and in patients with dandruff and seborrheic dermatitis, disorders characterized by increasing scaling. Three organisms were constantly found: (1) Pityrosporum, (2) aerobic cocci, and (3) Corynebacterium acnes. Pityrosporum (mainly Pityrosporum ovale) made up 46% of the total microflora in normals, 74% in dandruff, and 83% in seborvheic dermatitis. The geometric mean number of organisms per cm-2 in non-dandruff subjects was 5.04 times 10-5; 9.22 times 10-5 in dandruff subjects; and 6.45 times 10-5 in those with seborrheic dermatitis. The cocci were dominantly Baird-Parker type SII and no quantitative or qualitative change occurred in the scaling disorders. C. acnes comprised 26% of the flora on the normal scalp, 6% in dandruff, and only 1% in seborrheic dermatitis. These results differ significantly from previous reports which describe a much more complex microflora and suggest an etiologic role for microorganisms in dandruff. SN - 0022-202X UR - https://www.unboundmedicine.com/medline/citation/237965/Quantitative_microbiology_of_the_scalp_in_non_dandruff_dandruff_and_seborrheic_dermatitis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-202X(15)44527-0 DB - PRIME DP - Unbound Medicine ER -