Tags

Type your tag names separated by a space and hit enter

Alginate dressings for healing diabetic foot ulcers.

Abstract

BACKGROUND

Foot ulcers in people with diabetes mellitus are a common and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use.

OBJECTIVES

To compare the effects of alginate wound dressings with no wound dressing or alternative dressings on the healing of foot ulcers in people with diabetes mellitus.

SEARCH METHODS

For this first update, in April 2013, we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication.

SELECTION CRITERIA

Published or unpublished randomised controlled trials (RCTs) that have compared the effects on ulcer healing of alginate dressings with alternative wound dressings or no dressing in the treatment of foot ulcers in people with diabetes.

DATA COLLECTION AND ANALYSIS

Two review authors independently performed study selection, risk of bias assessment and data extraction.

MAIN RESULTS

We included six studies (375 participants) in this review; these compared alginate dressings with basic wound contact dressings, foam dressings and a silver-containing, fibrous-hydrocolloid dressing. Meta analysis of two studies found no statistically significant difference between alginate dressings and basic wound contact dressings: risk ratio (RR) 1.09 (95% CI 0.66 to 1.80). Pooled data from two studies comparing alginate dressings with foam dressings found no statistically significant difference in ulcer healing (RR 0.67, 95% CI 0.41 to 1.08). There was no statistically significant difference in the number of diabetic foot ulcers healed when an anti-microbial (silver) hydrocolloid dressing was compared with a standard alginate dressing (RR 1.40, 95% CI 0.79 to 2.47). All studies had short follow-up times (six to 12 weeks), and small sample sizes.

AUTHORS' CONCLUSIONS

Currently there is no research evidence to suggest that alginate wound dressings are more effective in healing foot ulcers in people with diabetes than other types of dressing however many trials in this field are very small. Decision makers may wish to consider aspects such as dressing cost and the wound management properties offered by each dressing type e.g. exudate management.

Links

  • Publisher Full Text
  • Authors+Show Affiliations

    ,

    Department of Nursing, Midwifery and Social Work, University of Manchester, Manchester, UK. jo.dumville@manchester.ac.uk.

    , ,

    Source

    MeSH

    Alginates
    Bandages
    Bandages, Hydrocolloid
    Diabetic Foot
    Humans
    Randomized Controlled Trials as Topic
    Silver Compounds
    Wound Healing

    Pub Type(s)

    Journal Article
    Meta-Analysis
    Research Support, Non-U.S. Gov't
    Review
    Systematic Review

    Language

    eng

    PubMed ID

    23799857

    Citation

    Dumville, Jo C., et al. "Alginate Dressings for Healing Diabetic Foot Ulcers." The Cochrane Database of Systematic Reviews, 2013, p. CD009110.
    Dumville JC, O'Meara S, Deshpande S, et al. Alginate dressings for healing diabetic foot ulcers. Cochrane Database Syst Rev. 2013.
    Dumville, J. C., O'Meara, S., Deshpande, S., & Speak, K. (2013). Alginate dressings for healing diabetic foot ulcers. The Cochrane Database of Systematic Reviews, (6), p. CD009110. doi:10.1002/14651858.CD009110.pub3.
    Dumville JC, et al. Alginate Dressings for Healing Diabetic Foot Ulcers. Cochrane Database Syst Rev. 2013 Jun 25;(6)CD009110. PubMed PMID: 23799857.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Alginate dressings for healing diabetic foot ulcers. AU - Dumville,Jo C, AU - O'Meara,Susan, AU - Deshpande,Sohan, AU - Speak,Katharine, Y1 - 2013/06/25/ PY - 2013/6/27/entrez PY - 2013/6/27/pubmed PY - 2013/11/20/medline SP - CD009110 EP - CD009110 JF - The Cochrane database of systematic reviews JO - Cochrane Database Syst Rev IS - 6 N2 - BACKGROUND: Foot ulcers in people with diabetes mellitus are a common and serious global health issue. Dressings form a key part of ulcer treatment, with clinicians and patients having many different types to choose from including alginate dressings. A clear and current overview of current evidence is required to facilitate decision-making regarding dressing use. OBJECTIVES: To compare the effects of alginate wound dressings with no wound dressing or alternative dressings on the healing of foot ulcers in people with diabetes mellitus. SEARCH METHODS: For this first update, in April 2013, we searched the following databases the Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL. There were no restrictions based on language or date of publication. SELECTION CRITERIA: Published or unpublished randomised controlled trials (RCTs) that have compared the effects on ulcer healing of alginate dressings with alternative wound dressings or no dressing in the treatment of foot ulcers in people with diabetes. DATA COLLECTION AND ANALYSIS: Two review authors independently performed study selection, risk of bias assessment and data extraction. MAIN RESULTS: We included six studies (375 participants) in this review; these compared alginate dressings with basic wound contact dressings, foam dressings and a silver-containing, fibrous-hydrocolloid dressing. Meta analysis of two studies found no statistically significant difference between alginate dressings and basic wound contact dressings: risk ratio (RR) 1.09 (95% CI 0.66 to 1.80). Pooled data from two studies comparing alginate dressings with foam dressings found no statistically significant difference in ulcer healing (RR 0.67, 95% CI 0.41 to 1.08). There was no statistically significant difference in the number of diabetic foot ulcers healed when an anti-microbial (silver) hydrocolloid dressing was compared with a standard alginate dressing (RR 1.40, 95% CI 0.79 to 2.47). All studies had short follow-up times (six to 12 weeks), and small sample sizes. AUTHORS' CONCLUSIONS: Currently there is no research evidence to suggest that alginate wound dressings are more effective in healing foot ulcers in people with diabetes than other types of dressing however many trials in this field are very small. Decision makers may wish to consider aspects such as dressing cost and the wound management properties offered by each dressing type e.g. exudate management. SN - 1469-493X UR - https://www.unboundmedicine.com/medline/citation/23799857/Alginate_dressings_for_healing_diabetic_foot_ulcers_ L2 - https://doi.org/10.1002/14651858.CD009110.pub3 DB - PRIME DP - Unbound Medicine ER -